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非小细胞肺癌患者胸腔镜微创术后复发转移的影响因素

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目的:分析非小细胞肺癌(NSCLC)患者胸腔镜微创术后复发转移的影响因素.方法:选取 2020 年 5 月至 2022 年 5 月在该院行胸腔镜微创手术治疗的 109 例NSCLC患者进行横断面研究.收集患者临床资料,术后随访 2 年观察复发转移情况,根据随访结果将其分为复发转移组与未复发转移组,对NSCLC患者胸腔镜微创术后复发转移的相关因素进行单因素分析和Logistic回归分析.结果:109例NSCLC患者胸腔镜微创术后复发转移24例,复发转移率为22.02%(24/109);两组性别、病灶部位、病理类型、肿瘤直径比较,差异均无统计学意义(P>0.05);复发转移组年龄≥60 岁、肿瘤分化程度为低分化、淋巴结转移数量≥10 个、发生纵隔淋巴结转移、术后未放化疗占比均高于未复发转移组,差异有统计学意义(P<0.05).Logistic回归分析结果显示,年龄≥60岁、肿瘤分化程度为低分化、淋巴结转移数量≥10 个、发生纵隔淋巴结转移、术后未放化疗均为NSCLC患者胸腔镜微创术后复发转移的危险因素(OR>1,P<0.05).结论:年龄≥60 岁、肿瘤分化程度为低分化、淋巴结转移数量≥10 个、发生纵隔淋巴结转移、术后未放化疗均为NSCLC患者胸腔镜微创术后复发转移的危险因素.
Influencing factors of recurrence and metastasis in patients with non-small cell lung cancer after thoracoscopic minimally invasive surgery
Objective:To analyze influencing factors of recurrence and metastasis in patients with non-small cell lung cancer(NSCLC)after thoracoscopic minimally invasive surgery.Methods:A cross-sectional study was conducted on 109 patients with NSCLC after thoracoscopic minimally invasive surgery admitted to this hospital from May 2020 to May 2022.The clinical data of these patients were collected.Recurrence and metastasis were evaluated 2 years after the surgery.According to whether there was recurrence and metastasis,they were divided into recurrence and metastasis group and non-recurrence and metastasis group.Logistic regression was used to analyze the influencing factors of recurrence and metastasis in the patients with NSCLC after thoracoscopic minimally invasive surgery.Results:There were 24 cases of recurrence and metastasis in the 109 patients with NSCLC after thoracoscopic minimally invasive surgery,and the recurrence and metastasis rate was 22.02%(24/109).There were no significant differences in gender,lesion location,pathological type and tumor diameter between the two groups(P>0.05).The proportions of the patients with age≥60 years old,poorly differentiated tumor differentiation,number of lymph node metastasis≥10,combined mediastinal lymph node metastasis,and no postoperative radiotherapy and chemotherapy in the recurrence and metastasis group were higher than those in the non-recurrence and metastasis group,and the differences were statistically significant(P<0.05).Logistic regression analysis showed that age≥60 years,poorly differentiated tumor,number of lymph node metastasis≥10,concomitant mediastinal lymph node metastases,and no postoperative radiotherapy or chemotherapy were all risk factors for recurrence and metastasis in the patients with NSCLC after thoracoscopic minimally invasive surgery(OR>1,P<0.05).Conclusions:Age≥60 years,poorly differentiated tumor,number of lymph node metastasis≥10,concomitant mediastinal lymph node metastases,and no postoperative radiotherapy or chemotherapy are the risk factors for recurrence and metastasis in the patients with NSCLC after thoracoscopic minimally invasive surgery.

Non-small cell lung cancerThoracoscopic minimally invasive surgeryRecurrence and metastasisInfluencing factor

赵敏政

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安阳市第二人民医院外一科,河南 安阳 455133

非小细胞肺癌 胸腔镜微创手术 复发转移 影响因素

2024

中国民康医学
中国社会工作协会

中国民康医学

影响因子:0.649
ISSN:1672-0369
年,卷(期):2024.36(6)
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