Influencing factors of recurrence and metastasis in patients with non-small cell lung cancer after thoracoscopic minimally invasive surgery
Objective:To analyze influencing factors of recurrence and metastasis in patients with non-small cell lung cancer(NSCLC)after thoracoscopic minimally invasive surgery.Methods:A cross-sectional study was conducted on 109 patients with NSCLC after thoracoscopic minimally invasive surgery admitted to this hospital from May 2020 to May 2022.The clinical data of these patients were collected.Recurrence and metastasis were evaluated 2 years after the surgery.According to whether there was recurrence and metastasis,they were divided into recurrence and metastasis group and non-recurrence and metastasis group.Logistic regression was used to analyze the influencing factors of recurrence and metastasis in the patients with NSCLC after thoracoscopic minimally invasive surgery.Results:There were 24 cases of recurrence and metastasis in the 109 patients with NSCLC after thoracoscopic minimally invasive surgery,and the recurrence and metastasis rate was 22.02%(24/109).There were no significant differences in gender,lesion location,pathological type and tumor diameter between the two groups(P>0.05).The proportions of the patients with age≥60 years old,poorly differentiated tumor differentiation,number of lymph node metastasis≥10,combined mediastinal lymph node metastasis,and no postoperative radiotherapy and chemotherapy in the recurrence and metastasis group were higher than those in the non-recurrence and metastasis group,and the differences were statistically significant(P<0.05).Logistic regression analysis showed that age≥60 years,poorly differentiated tumor,number of lymph node metastasis≥10,concomitant mediastinal lymph node metastases,and no postoperative radiotherapy or chemotherapy were all risk factors for recurrence and metastasis in the patients with NSCLC after thoracoscopic minimally invasive surgery(OR>1,P<0.05).Conclusions:Age≥60 years,poorly differentiated tumor,number of lymph node metastasis≥10,concomitant mediastinal lymph node metastases,and no postoperative radiotherapy or chemotherapy are the risk factors for recurrence and metastasis in the patients with NSCLC after thoracoscopic minimally invasive surgery.
Non-small cell lung cancerThoracoscopic minimally invasive surgeryRecurrence and metastasisInfluencing factor