Effects of low frequency pulse electrical stimulation combined with antibiotics in treatment of patients with chronic pelvic inflammatory disease
Objective:To explore effects of low frequency pulse electrical stimulation combined with antibiotics in treatment of patients with chronic pelvic inflammatory disease.Methods:A prospective study was conducted on 80 patients with chronic pelvic inflammatory disease admitted to the hospital from February 2021 to February 2023.They were divided into control group and observation group by odd and even number method,40 cases in each group.The control group was treated with antibiotics,while the observation group was treated with low frequency pulse electrical stimulation on the basis of that of the control group.The treatment effects,the disappearance time of clinical symptoms,the hospitalization time,the pelvic hemodynamic indexes[pulsatility index(PI),resistance index(RI),peak systolic velocity(PSV)]levels,the levels of inflammatory factors[transforming growth factor-β1(TGF-β1),macrophage chemoattractant protein-1(MCP-1),interleukin-1β(IL-1β),granulocyte-macrophage colony-stimulating factor(GM-CSF)]before and after the treatment,and the incidence of adverse reactions during treatment were compared between the two groups.Results:The total effective rate of the observation group was 90.00%(36/40),which was higher than 72.50%(29/40)of the control group,and the difference was statistically significant(P<0.05).The disappearance time of abdominal pain,the disappearance time of abdominal bulge and the hospitalization time in the observation group were shorter than those in the control group,and the differences were statistically significant(P<0.05).After the treatment,the PI and RI of ovarian artery and uterine artery in the observation group were lower than those in the control group,the PSV was higher than that in the control group,and the differences were statistically significant(P<0.05).The level of TGF-β1 in the observation group was higher than that in the control group,the levels of MCP-1,GM-CSF and IL-1β were lower than those in the control group,the and differences were statistically significant(P<0.05).However,there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions:Low frequency pulse electrical stimulation combined with antibiotics in the treatment of the patients with chronic pelvic inflammatory disease can improve the total effective rate of treatment,improve the levels of pelvic hemodynamic indexes and inflammatory factors,shorten the disappearance time of clinical symptoms and the hospitalization time.Moreover,it is superior to single antibiotic treatment.
万方数据
维普
