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抗精神病药联用致恶性综合征2例临床分析

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目的:分析 2 例抗精神病药联用致恶性综合征病例.方法:回顾性分析该院收治的 2 例抗精神病药联用致恶性综合征患者的临床资料.结果:2 例患者均为精神分裂症,在接受 2 种抗精神病药联合治疗后出现发热、肌强直、肌酸激酶水平升高等表现,确诊恶性综合征后立即停用抗精神病药物,经有效治疗病情缓解后出院.结论:恶性综合征患者主要临床表现为发热、肌强直、肌酸激酶水平升高,早诊早治可改善其预后.
Clinical analysis of 2 cases of malignant syndrome caused by antipsychotic drugs
Objective:To analyze 2 cases of malignant syndrome caused by antipsychotic drugs.Methods:The clinical data of 2 patients with malignant syndrome caused by antipsychotic drugs in this hospital were retrospectively analyzed.Results:The two patients were both schizophrenics.After receiving the combination treatment of two antipsychotic drugs,they developed fever,myotonia,and elevated creatine kinase levels.The antipsychotic drugs were discontinued immediately after the diagnosis of malignant syndrome,and these patient was discharged after effective treatment.Conclusions:The main clinical manifestations of the patients with malignant syndrome are fever,myotonia,and elevated creatine kinase levels.Early diagnosis and treatment can improve their prognosis.

Malignant syndromeAntipsychotic drugSchizophreniaPrognosisAnalysis

廖美妹

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广西壮族自治区脑科医院,广西 柳州 545005

恶性综合征 抗精神病药物 精神分裂症 预后 分析

2024

中国民康医学
中国社会工作协会

中国民康医学

影响因子:0.649
ISSN:1672-0369
年,卷(期):2024.36(6)
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