Influencing factors of pregnancy failure after tocolytic therapy in elderly pregnant women with threatened abortion in early pregnancy
Objective:To analyze influencing factors of pregnancy failure after tocolytic therapy in elderly pregnant women with threatened abortion in early pregnancy.Methods:A cross-sectional study was conducted on 230 elderly pregnant women with threatened abortion in early pregnancy admitted to this hospital from January 2021 to January 2023.All patients were treated with tocolytic therapy,and the pregnancy outcome was determined.According to the pregnancy outcome,they were divided into continued pregnancy group and pregnancy failure group.Logistic regression was used to analyze the influencing factors of pregnancy failure after tocolytic therapy in the elderly pregnant women with threatened abortion in early pregnancy.Results:There were 45 cases of pregnancy failure after tocolytic therapy in the 230 elderly pregnant women with threatened abortion in early pregnancy,with an incidence of 19.57%(45/230).There were no significant differences in age,gestational age,gravidity,pre-pregnancy body mass index,history of induced abortion,history of premature delivery,history of smoking during pregnancy,history of drinking during pregnancy,and combined vaginitis between the two groups(P>0.05).The proportions of the cases with luteal insufficiency,history of spontaneous abortion,large intrauterine hematoma,and β-human chorionic gonadotropin(β-hCG)<9000 mU/mL in the pregnancy failure group were higher than those in the continuous pregnancy group,and the differences were statistically significant(P<0.05).Logistic regression analysis showed that luteal insufficiency,history of spontaneous abortion,large intrauterine hematoma,and β-hCG<9000 mU/mL were risk factors for pregnancy failure after tocolytic therapy in the elderly pregnant women with threatened abortion in early pregnancy(OR>1,P<0.05).Conclusions:Luteal insufficiency,history of spontaneous abortion,large intrauterine hematoma,and β-hCG<9000 mU/mL are the risk factors for pregnancy failure after tocolytic therapy in the elderly pregnant women with threatened abortion in early pregnancy.
Early pregnancyThreatened abortionElderlyPregnant womanTocolytic therapyPregnancy failureInfluencing factor