Effects of invasive-noninvasive sequential mechanical ventilation on elderly patients with severe pneumonia
Objective:To observe effects of invasive-noninvasive sequential mechanical ventilation on elderly patients with severe pneumonia.Methods:A prospective study was conducted on 80 elderly patients with severe pneumonia admitted to the hospital from March 2022 to May 2023.They were divided into control group and observation group by using the random number table method,40 cases in each group.The control group received invasive mechanical ventilation treatment,while the observation group received invasive-noninvasive sequential mechanical ventilation treatment.The levels of pulmonary ventilation indicators[forced vital capacity(FVC),forced expiratory volume in one second(FEV1),peak expiratory flow(PEF),FEV1/FVC,mean pulmonary artery pressure(mPVP)],and blood gas analysis indicators[arterial partial pressure of carbon dioxide(PaCO2),arterial oxygen pressure(PaO2),pH value]before and after the treatment,the incidence of ventilator associated pneumonia(VAP),and the extubation success rate were compared between two groups.Results:After the treatment,the levels of FVC,FEV1,FEV1/FVC,and PEF in both groups were higher than those before the treatment,and those in the observation group were higher than those in the control group;the levels of mPVP in both groups was lower than those before the treatment,and that in the observation group was lower than that in the control group;and the differences were statistically significant(P<0.05).The pH value and levels of PaO2 in both groups were higher than those before the treatment,and those in the observation group were higher than those in the control group;the PaCO2 levels in both groups were lower than those before the treatment,and that in the observation group was lower than that in the control group;and the differences were statistically significant(P<0.05).Further,the incidence of VAP in the observation group was lower than that in the control group,the one-time extubation success rate was higher than that in the control group,and the differences were statistically significant(P<0.05).Conclusions:Invasive-noninvasive sequential mechanical ventilation can effectively improve the levels of lung ventilation indicators and blood gas analysis indicators,reduce the incidence of VAP,and increase the one-time extubation success rate in the elderly patients with severe pneumonia.Moreover,it is superior to invasive mechanical ventilation treatment.
NETL
NSTL
万方数据
维普
