Application effects of Dexmedetomidine combined with Ropivacaine transversus abdominis plane block in patients undergoing peritoneal dialysis catheterization
Objective:To observe application effects of Dexmedetomidine combined with Ropivacaine transversus abdominis plane block(TAPB)in patients undergoing peritoneal dialysis catheterization.Methods:A prospective study was conducted on 101 patients who underwent peritoneal dialysis catheterization in the hospital from February 2019 to February 2021.According to the random number table method,they were divided into control group(n=50)and observation group(n=51).The control group was treated with Ropivacaine TAPB,while the observation group was treated with Dexmedetomidine combined with Ropivacaine TAPB.The levels of anesthesia-related indicators(onset time and duration of anesthesia),the pain[visual analogue scale(VAS)]score,and the sedation(Ramsay score)scores at 2,4,6 h after the surgery,the stress indicator levels[cortisol(Cor),norepinephrine(NE),epinephrine(E)]before and after the surgery,and the incidence of adverse reactions were compared between the two groups.Results:The onset time of anesthesia in the observation group was shorter than that in the control group,the duration was longer than that in the control group,and the differences were statistically significant(P<0.05).2,4,6 h after the surgery,the VAS scores of the observation group were lower than those of the control group,the Ramsay scores were higher than those of the control group,and the differences were statistically significant(P<0.05).After the surgery,the levels of Cor,E and NE in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).However,there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions:Dexmedetomidine combined with Ropivacaine TAPB in the patients undergoing peritoneal dialysis catheterization can improve the levels of anesthesia-related indicators,reduce the postoperative pain scores and the stress indicator levels,and improve the postoperative sedation scores.Moreover,it is superior to single Ropivacaine TAPB.
NETL
NSTL
万方数据
维普
