Application effects of patient-controlled epidural analgesia in painless labor of primipara
Objective:To observe application effects of patient-controlled epidural analgesia(PCEA)in painless labor of primipara.Methods:A prospective study was conducted on 156 primiparas admitted to the hospital from April 2020 to April 2022.According to the random number table method,they were divided into control group and study group,78 cases in each group.The control group was treated with patient-controlled intravenous analgesia,while the study group was treated with PCEA.The total stage of labor,the postpartum hemorrhage volume,the hospitalization time,the pain degree[visual analogue scale(VAS)]scores at different time[before analgesia(T0),20 min after analgesia(T1),full opening of cervix(T2),immediately after delivery(T3)],the levels of coagulation function indexes[activated partial thromboplastin time(APTT),prothrombin time(TT),fibrinogen(FIB)]and oxidative stress indexes[advanced oxidation protein product(AOPP),glutathione peroxidase(GSH-Px),catalase(CAT)]before and after delivery,and the neonatal Apgar score were compared between the two groups.Results:The total stage of labor and the hospitalization time in the study group were shorter than those in the control group,the postpartum hemorrhage volume was less than that in the control group,and the differences were statistically significant(P<0.05).At T1,T2 and T3,the VAS scores of the two groups were lower than those at T0,those in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).After delivery,the levels of coagulation function indexes such as APTT,PT in the two groups were longer than those before delivery,those in the study group were longer than those in the control group,and FIB in the two groups were higher than those before delivery,that in the study group was higher than that in the control group,and the differences were statistically significant(P<0.05).The levels of GSH-Px,CAT and AOPP in the two groups were higher than those before delivery,but those in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).Further,the neonatal Apgar score of the study group was higher than the control group,and the difference was statistically significant(P<0.05).Conclusions:The PCEA in painless labor of primipara can shorten the total stage of labor and the hospitalization time,reduce the postpartum hemorrhage volume,relieve the maternal pain,improve the coagulation function,reduce the body's oxidative stress response,and improve the Apgar score of newborns.Moreover,it is superior to patient-controlled intravenous analgesia.
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NSTL
万方数据
维普
