首页|血塞通注射液联合气压治疗仪在脑梗死偏瘫患者中的应用效果

血塞通注射液联合气压治疗仪在脑梗死偏瘫患者中的应用效果

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目的:观察血塞通注射液联合气压治疗仪在脑梗死偏瘫患者中的应用效果.方法:选取 2020 年 8 月至 2022 年 9 月该院收治的 103 例脑梗死偏瘫患者进行前瞻性研究,按随机数字表法将其分为对照组 51 例与观察组 52 例.对照组采用气压治疗仪治疗,观察组在对照组基础上联合血塞通注射液治疗,比较两组下肢深静脉血栓发生率,治疗前后股静脉血流水平、凝血功能指标[凝血酶原时间(PT)、活化部分凝血酶原时间(APTT)、D-二聚体(D-D)]水平、肢体运动功能[Fugl-Meyer运动功能量表(FMA)]评分、神经功能缺损程度[美国国立卫生研究院卒中量表(NIHSS)]评分,以及不良反应发生率.结果:观察组下肢深静脉血栓发生率为 5.77%(3/52),低于对照组的21.57%(11/51),差异有统计学意义(P<0.05);治疗后,两组股静脉血流平均速度、血流峰速度均高于治疗前,且观察组高于对照组,差异有统计学意义(P<0.05);两组PT、APTT均长于对照组,且观察组长于对照组,两组D-D水平均高于治疗前,且观察组高于对照组,差异有统计学意义(P<0.05);两组FMA评分均高于治疗前,且观察组高于对照组,两组NIHSS评分均低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05);治疗期间,两组均未发生明显不良反应.结论:血塞通注射液联合气压治疗仪预防脑梗死偏瘫患者下肢深静脉血栓效果显著,可改善凝血功能指标水平,降低神经功能缺损程度,提高运动功能,其效果优于单纯气压治疗仪治疗.
Application effects of Xuesaitong injection combined with pressure therapy instrument in patients with cerebral infarction hemiplegia
Objective:To observe application effects of Xuesaitong injection combined with pressure therapy instrument in patients with cerebral infarction hemiplegia.Methods:A prospective study was conducted on 103 patients with cerebral infarction hemiplegia admitted to this hospital from August 2020 to September 2022.According to the random number table method,they were divided into control group(51 cases)and observation group(52 cases).The control group was treated with pressure therapy instrument,while the observation group was treated with Xuesaitong injection on the basis of that of the control group.The incidence of lower extremity deep venous thrombosis,the femoral vein blood flow levels before and after the treatment,the coagulation function index[prothrombin time(PT),activated partial thromboplastin time(APTT),D-dimer(D-D)]levels,the limb motor function[Fugl-Meyer motor assessment(FMA)]score,the neurological deficit degree[National Institutes of Health stroke scale(NIHSS)]score,and the incidence of adverse reactions were compared between the two groups.Results:The incidence of lower extremity deep vein thrombosis in the observation group was 5.77%(3/52),which was lower than 21.57%(11/51)in the control group,and the difference was statistically significant(P<0.05).After the treatment,the average velocity and peak velocity levels of femoral vein blood flow in the two groups were higher than those before the treatment,those in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).The the levels PT,APTT in the two groups were longer than those before the treatment,those in the observation group were longer than those in the control group,and D-D in the two groups were higher than those before the treatment,those in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).The FMA scores of the two groups were higher than those before the treatment,and that in the observation group was higher than that in the control group;the NIHSS scores of the two groups were lower than those before the treatment,and that in the observation group was lower than that in the control group;and the differences were statistically significant(P<0.05).During the treatment,there were no obvious adverse reactions in the two groups.Conclusions:Xuesaitong injection combined with pressure therapy instrument has a significant effect on preventing lower extremity deep venous thrombosis in the patients with cerebral infarction hemiplegia,which can improve the levels of coagulation function indexes,reduce the degree of neurological deficit and improve the motor function.Moreover,it is superior to simple pressure therapy instrument intervention.

Cerebral infarction hemiplegiaLower extremity deep venous thrombosisXuesaitong InjectionPressure therapy instrumentFemoral vein blood flowCoagulation function

何春磊、张帅杰

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漯河医学高等专科学校第二附属医院神经内二科,河南 漯河 462300

脑梗死偏瘫 下肢深静脉血栓 血塞通注射液 气压治疗仪 股静脉血流 凝血功能

2024

中国民康医学
中国社会工作协会

中国民康医学

影响因子:0.649
ISSN:1672-0369
年,卷(期):2024.36(7)
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