Application effects of Xuesaitong injection combined with pressure therapy instrument in patients with cerebral infarction hemiplegia
Objective:To observe application effects of Xuesaitong injection combined with pressure therapy instrument in patients with cerebral infarction hemiplegia.Methods:A prospective study was conducted on 103 patients with cerebral infarction hemiplegia admitted to this hospital from August 2020 to September 2022.According to the random number table method,they were divided into control group(51 cases)and observation group(52 cases).The control group was treated with pressure therapy instrument,while the observation group was treated with Xuesaitong injection on the basis of that of the control group.The incidence of lower extremity deep venous thrombosis,the femoral vein blood flow levels before and after the treatment,the coagulation function index[prothrombin time(PT),activated partial thromboplastin time(APTT),D-dimer(D-D)]levels,the limb motor function[Fugl-Meyer motor assessment(FMA)]score,the neurological deficit degree[National Institutes of Health stroke scale(NIHSS)]score,and the incidence of adverse reactions were compared between the two groups.Results:The incidence of lower extremity deep vein thrombosis in the observation group was 5.77%(3/52),which was lower than 21.57%(11/51)in the control group,and the difference was statistically significant(P<0.05).After the treatment,the average velocity and peak velocity levels of femoral vein blood flow in the two groups were higher than those before the treatment,those in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).The the levels PT,APTT in the two groups were longer than those before the treatment,those in the observation group were longer than those in the control group,and D-D in the two groups were higher than those before the treatment,those in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).The FMA scores of the two groups were higher than those before the treatment,and that in the observation group was higher than that in the control group;the NIHSS scores of the two groups were lower than those before the treatment,and that in the observation group was lower than that in the control group;and the differences were statistically significant(P<0.05).During the treatment,there were no obvious adverse reactions in the two groups.Conclusions:Xuesaitong injection combined with pressure therapy instrument has a significant effect on preventing lower extremity deep venous thrombosis in the patients with cerebral infarction hemiplegia,which can improve the levels of coagulation function indexes,reduce the degree of neurological deficit and improve the motor function.Moreover,it is superior to simple pressure therapy instrument intervention.
Cerebral infarction hemiplegiaLower extremity deep venous thrombosisXuesaitong InjectionPressure therapy instrumentFemoral vein blood flowCoagulation function