Effects of Jianpi Yixin formula combined with Amiodarone hydrochloride in treatment of elderly patients with chronic arrhythmia
Objective:To observe effects of Jianpi Yixin formula combined with Amiodarone hydrochloride in treatment of elderly patients with chronic arrhythmia.Methods:A prospective study was conducted on 80 elderly patients with chronic arrhythmia admitted to the hospital from January 2022 to January 2023.According to the coin tossing method,they were divided into control group and observation group,40 cases in each group.The control group was treated with Amiodarone hydrochloride tablets,while the observation group was treated with Jianpi Yixin formula on the basis of that of the control group.The clinical efficacy,the TCM syndrome scores,the cardiac function indexes[stroke volume(SV),left ventricular ejection fraction(LVEF)]levels,the biochemical indexes[C-reactive protein(CRP),homocysteine(Hcy),diuretic peptide(BNP)]levels before and after the treatment,and the incidence of adverse reactions during the treatment were compared between the two groups.Results:The total effective rate of treatment in the observation group was 90.00%(36/40),which was higher than 72.50%(29/40)in the control group,and the difference was statistically significant(P<0.05).After the treatment,the scores of TCM syndromes such as palpitation,limb fatigue,insomnia and dreaminess,abdominal distension and loose stools in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).After the treatment,the levels of SV and LVEF in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).After the treatment,the levels of CRP,Hcy and BNP in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05).However,there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions:Jianpi Yixin formula combined with Amiodarone hydrochloride in the treatment of the elderly patients with chronic arrhythmia can improve the total treatment efficiency and the cardiac function index levels,and reduce the TCM syndrome scores and the biochemical index levels.Moreover,it is superior to single Amiodarone hydrochloride tablets.
NETL
NSTL
万方数据
维普
