Effects of invasive mechanical ventilation-high flow oxygen therapy sequential therapy on patients with severe pneumonia complicated with severe respiratory failure
Objective:To observe effects of invasive mechanical ventilation-high flow oxygen therapy sequential therapy on patients with severe pneumonia complicated with severe respiratory failure.Methods:A prospective study was conducted on 70 patients with severe pneumonia complicated with severe respiratory failure admitted to the hospital from 2019 to 2022.According to the random number table method,they were divided into study group and control group,35 cases in each group.Both groups were given symptomatic treatment.On this basis,the control group was treated with invasive-noninvasive mechanical ventilation sequential therapy,while the study group was treated with invasive mechanical ventilation-high flow oxygen therapy sequential therapy.The levels of blood gas analysis indexes[pH value,arterial partial pressure of carbon dioxide(PaCO2),oxygenation index(OI)],the dyspnea(Borg dyspnea score scale)score,the ICU stay time,the 28-day mortality,and the complication rate were compared between the two groups before and after the treatment.Results:After the treatment,the pH value and OI level of the study group were higher than those of the control group,the PaCO2 level was lower than that of the control group,and the differences were statistically significant(P<0.05).After the treatment,the Borg dyspnea score of the study group was lower than that of the control group,and the difference was statistically significant(P<0.05).However,there were no significant differences in the ICU stay time,the 28-day mortality and the complication rate between the two groups(P>0.05).Conclusions:Invasive mechanical ventilation-high flow oxygen therapy sequential therapy can improve the levels of blood gas analysis indexes the and reduce dyspnea scores in the patients with severe pneumonia complicated with severe respiratory failure.Moreover,it is superior to invasive-noninvasive mechanical ventilation sequential therapy.
NETL
NSTL
万方数据
维普
