Effects of Dingpeng cream combined with Cydiodine buccal tablets in treatment of gingivitis
Objective:To observe effects of Dingpeng cream combined with Cydiodine buccal tablets in treatment of gingivitis patients.Methods:A prospective study was conducted on 88 patients with gingivitis admitted to this hospital from October 2020 to July 2022.They were divided into control group(n=44)and study group(n=44)by using the random number method.The control group was treated with Cydiodine buccal tablets,while the study group was treated with Dingpeng cream on the basis of that of the control group.The clinical efficacy,the periodontal related indexes[gingival index(GI),sulcus bleeding index(SBI),plaque index(PLI)]levels,the inflammatory factors[interleukin(IL)-1,IL-17,tumor necrosis factor-α(TNF-α),transforming growth factor-β(TGF-β)]levels before and after the treatment,and the incidence of adverse reactions were compared between the two groups.Results:The total effective rate of the study group was 93.18%(41/44),which was higher than 72.73%(32/44)of the control group,and the difference was statistically significant(P<0.05).After the treatment,the scores of GI,PLI and SBI in the two groups were lower than those before the treatment,those in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).The levels of IL-1,IL-17,TNF-α and TGF-β in the two groups were lower than those before the treatment,those in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).However,there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions:Dingpeng cream combined with Cydiodine buccal tablets in the treatment of the gingivitis patients can improve the total effective rate of treatment and reduce the levels of periodontal related indexes and inflammatory factors.Moreover,it is superior to single Cydiodine buccal tablets treatment.