Comparison of efficiencies of enzyme-linked immunosorbent assay and Toluidine red unheated serum test in diagnosis of treponema pallidum infection
Objective:To compare efficiencies of enzyme-linked immunosorbent assay(ELISA)and Toluidine red unheated serum test(TRUST)in diagnosis of Treponema pallidum infection.Methods:100 patients with suspected Treponema pallidum infection who were tested for infectious diseases in the center from June 2021 to June 2022 were selected as the research objects.Blood samples were collected from these patients.ELISA,TRUST and Treponema pallidum gelatin agglutination test were performed.Using the results of Treponema pallidum gelatin agglutination test as the gold standard,the efficiencies of ELISA and TRUST in the diagnosis of Treponema pallidum infection were compared.Results:Among the 100 cases of suspected Treponema pallidum infection,Treponema pallidum gelatin agglutination test showed positive in 63 cases and negative in 37 cases;ELISA test showed positive in 62 cases and negative in 38 cases;and TRUST test showed positive in 56 cases and negative in 44 cases.The sensitivity,the accuracy and the negative predictive value of ELISA in the diagnosis of Treponema pallidum infection were higher than those of TRUST,the missed diagnosis rate was lower than that of TRUST,and the differences were statistically significant(P<0.05).Conclusions:The efficiency of ELISA in the diagnosis of Treponema pallidum infection is higher than that of TRUST.
NETL
NSTL
万方数据
维普
