Value of combined detection of cystatin C,serum creatinine,UACR and urea nitrogen levels in diagnosis of renal function injury in patients with metabolic syndrome
Objective:To explore value of combined detection of serum cystatin C,serum creatinine,urinary albumin to creatinine ratio(UACR)and urea nitrogen in diagnosis of renal function injury in patients with metabolic syndrome.Methods:The clinical data of 200 patients with metabolic syndrome admitted to this hospital from October 2022 to April 2023 were analyzed.According to whether the renal function was damaged,they were divided into normal group and injury group,100 cases in each group.The levels of serum cystatin C,serum creatinine,urinary creatinine and UACR were compared between the two groups.The receiver operating characteristic(ROC)curve was used to analyze the value of single and combined detection of cystatin C,serum creatinine,UACR and urea nitrogen levels in the diagnosis of renal function injury in the patients with metabolic syndrome.Results:The levels of serum cystatin C,serum creatinine,UACR and urea nitrogen in the injury group were higher than those in the normal group,and the differences were statistically significant(P<0.05).ROC curve results showed that the area under the curve(AUC)of combined detection of serum cystatin C,serum creatinine,UACR and urea nitrogen levels in the diagnosis of renal function injury in the patients with metabolic syndrome was 0.965,which was higher than that of each single detection(AUC = 0.637,0.683,0.752,0.623,P<0.05).Conclusions:The value of combined detection of serum cystatin C,serum creatinine,UACR and urea nitrogen levels in the diagnosis of renal function injury in the patients with metabolic syndrome is higher than that of each single detection.
Cystatin-CSerum creatinineUrea nitrogenMetabolic syndromeRenal function damage
NETL
NSTL
万方数据
维普
