Diagnostic efficiency of serum thyroid stimulating hormone,free triiodothyronine and serum free thyroxine in vascular stenosis of patients with cerebral infarction
Objective:To analyze diagnostic efficiency of serum thyroid stimulating hormone(TSH),free triiodothyronine(FT3)and serum free thyroxine(FT4)in vascular stenosis in patients with cerebral infarction.Methods:The clinical data of 100 patients with cerebral infarction admitted to this hospital from March 2022 to March 2023 were retrospectively analyzed.According to the north American symptomatic carotid endarterectomy(NASCET)stenosis measurement criteria,these patients with different degrees of cerebrovascular stenosis were divided into severe stenosis group(n=48)and mild stenosis group(n=52).The clinical data of 100 healthy subjects were chosen and they were set as the control group.The serum TSH,FT3 and FT4 levels were compared between the three groups of subjects.The correlations among the serum TSH,FT3,FT4 levels and the degree of vascular stenosis in the patients with cerebral infarction were analyzed by bivariate correlation tau-(K).The receiver operating characteristic(ROC)curve was drawn to analyze the diagnostic efficiencies of the serum TSH,FT3 and FT4 levels in the degree of vascular stenosis in the patients with cerebral infarction.Results:The levels of TSH and FT4 in the severe stenosis group were higher than those in the mild stenosis group and the control group,and those in the mild stenosis group were higher than those in the control group;the level of FT3 was lower than that in the mild stenosis group and the control group,and that in the mild stenosis group was lower than that in the control group;and the differences were statistically significant(P<0.05).The bivariate correlation tau-(K)showed that the serum TSH and FT4 levels were positively correlated with the degree of vascular stenosis(r>0,P<0.05),while the FT3 level was negatively correlated with the degree of vascular stenosis in patients with cerebral infarction(r<0,P<0.05).ROC curve results showed that the AUC of serum TSH,FT3,FT4 and combined detection for diagnosing cerebrovascular stenosis in patients with cerebral infarction were 0.815,0.810,0.815 and 0.895,respectively,and the diagnostic efficacy of combined detection was higher than that of the three single detection.Conclusions:The serum TSH and FT4 levels are positively correlated with the degree of vascular stenosis in the patients with cerebral infarction,while the serum FT3 level is negatively correlated with the degree of vascular stenosis The efficiency of combined detection of the serum TSH,FT3 and FT4 levels in the diagnosis of vascular stenosis in the patients with cerebral infarction ss higher than that of single detection of the three.
NETL
NSTL
万方数据
维普
