Correlations among serum cholinesterase,glutamyl transferase levels and liver function in patients with viral hepatitis
Objective:To analyze correlations among serum cholinesterase(CHE)and glutamyl transferase(GGT)levels and liver function in patients with viral hepatitis.Methods:The clinical data of 100 patients with viral hepatitis admitted to this hospital from January 2021 to August 2022 were retrospectively analyzed and they were as the study group,and the data of 100 healthy subjects during the same period were retrospectively analyzed and they were as selected as the control group.The levels of serum CHE and GGT in the two groups were detected.The liver function of these patients with viral hepatitis was evaluated by Child-Pugh classification.The serum CHE and GGT levels were compared between the two groups and the patients with viral hepatitis of different Child-Pugh classifications.The correlations among the serum CHE and GGT levels and liver function in the patients with viral hepatitis were analyzed by Kendall's tau-b correlation coefficient.Results:The serum GGT level of the study group was higher than that of the control group,the CHE level was lower than that of the control group,and the differences were statistically significant(P<0.05).The level of the serum GGT in the patients with Child-Pugh classification C viral hepatitis was higher than that in patients with Child-Pugh classification A and B,and that in the patients with classification B was higher than that in the patients with classification A;the level of the serum CHE in the patients with Child-Pugh classification C viral hepatitis was lower than that in patients with Child-Pugh classification A and B,and that in the patients with classification B was lower than that in the patients with classification A;and the differences were statistically significant(P<0.05).The Kendall's tau-b correlation coefficient analysis showed that serum CHE level was positively correlated with the liver function in the patients with viral hepatitis(r>0,P<0.05),while the serum GGT level was negatively correlated with the liver function(r<0,P<0.05).Conclusions:The serum CHE level is positively correlated with the liver function in the patients with viral hepatitis,while the serum GGT level is negatively correlated with the liver function.