Effects of Dexmedetomidine combined with Ropivacaine for transversus abdominis plane block-assisted general anesthesia on postoperative recovery of obese patients
Objective:To investigate effects of Dexmedetomidine combined with Ropivacaine for transversus abdominis plane block(TAPB)-assisted general anesthesia on recovery of obese patients after laparoscopic vertical banded gastroplasty.Methods:A prospective study was conducted on 115 obese patients who underwent laparoscopic vertical banded gastroplasty in this hospital from January 2021 to June 2022.According to the random number table method,they were divided into study group(n=58)and control group(n=57).Conventional intravenous general anesthesia was used in both groups,and ultrasound-guided bilateral TAPB was performed after anesthesia induction.The control group was treated with Ropivacaine for TAPB,while the study group was treated with Dexmedetomidine combined with Ropivacaine for TAPB.The anesthesia recovery indexes(wake-up time,spontaneous breathing recovery time and extubation time),the dosage of Sufentanil and Propofol during the surgery,the mean arterial pressure(MAP)and heart rate during perioperative period[after anesthesia induction(T1),immediately after the surgery(T2),immediately after extubation(T3),10 min after extubation(T4)],and the incidence of adverse reactions were compared between the two groups.Results:The wake up time,the spontaneous breathing recovery time and the extubation time of the study group were shorter than those of the control group,and the differences were statistically significant(P<0.05).The dosage of Sufentanil and Propofol in the study group was less than that in the control group,and the difference was statistically significant(P<0.05).At T1,there were no significant differences in the MAP and the heart rate between the two groups(P>0.05).At T2,T3 and T4,the levels of MAP and heart rate in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).The incidence of adverse reactions in the observation group was 8.62%(5/58),which was lower than 22.81%(13/57)in the control group,and the difference was statistically significant(P<0.05).Conclusions:Dexmedetomidine combined with Ropivacaine for TAPB in the obese patients undergoing laparoscopic vertical banded gastroplasty can reduce the dosage of intravenous anesthetics,shorten the postoperative wake up time,the spontaneous breathing recovery time and the extubation time,reduce the incidence of adverse reactions,and maintain the postoperative hemodynamic stability.Moreover,it is superior to single Ropivacaine for TAPB.
万方数据
维普
