Comparison of effects of ultrasound-guided radiofrequency ablation and endoscopic thyroidectomy in treatment of patients with benign thyroid nodules
Objective:To compare effects of ultrasound-guided radiofrequency ablation and endoscopic thyroidectomy in treatment of patients with benign thyroid nodules.Methods:A prospective study was conducted on 124 patients with benign thyroid nodules admitted to the hospital from May 2021 to May 2022.They were divided into observation group(n=62)and control group(n=62)by using the random number table method.The control group was treated with endoscopic thyroidectomy,while the observation group was treated with ultrasound-guided radiofrequency ablation.The levels of surgery-related indicators,inflammatory factors[C-reactive protein(CRP),interleukin-6(IL-6),procalcitonin(PCT)]and thyroid function indicators[thyroid stimulating hormone(TSH),free triiodothyronine(FT3),free thyroxine(FT4)]before and after the surgery,the incidence of complications,and the recurrence rate were compared between the two groups.Results:The operation time and the incision length of the observation group were shorter than those of the control group,the intraoperative blood loss was less than that of the control group,and the differences were statistically significant(P<0.05).One day after the surgery,the levels of serum CRP,IL-6 and PCT in the two groups were higher than those before the surgery,but those in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).One month after the surgery,the serum TSH levels of the two groups were higher than those before the surgery,but that in the observation group was lower than that in the control group;the levels of serum FT3 and FT4 in the two groups were lower than those before the surgery,but those in the observation group were higher than those in the control group;and the differences were statistically significant(P<0.05).However,there were no significant differences in the incidence of complications and recurrence rate between the two groups(P>0.05).Conclusions:Ultrasound-guided radiofrequency ablation in the treatment of the patients with benign thyroid nodules can reduce the levels of surgery-related indicators and inflammatory factors,and improve the levels of thyroid function indicators.Moreover,it is superior to endoscopic thyroidectomy.
万方数据
维普
