Effects of rTMS in treatment of patients with hemiplegia after cerebral infarction
Objective:To observe effects of repetitive transcranial magnetic stimulation(rTMS)on patients with hemiplegia after cerebral infarction.Methods:The clinical data of 96 patients with hemiplegia after cerebral infarction admitted to this hospital from January 2021 to January 2023 were retrospectively analyzed.According to the different treatment plans,they were divided into observation group and control group,48 cases in each group.The control group was given routine treatment,while the observation group was given rTMS treatment on the basis of that of the control group.The clinical efficacy,the National Institutes of Health stroke scale(NIHSS)score,the Fugl-Meyer motor assessment(FMA)score,the Barthel index(BI)score,the serum neurological function indexes[brain natriuretic peptide(BNP),S100β protein,neuron-specific enolase(NSE)]levels,the serum inflammatory factors[interleukin-6(IL-6),tumor necrosis factor-α(TNF-α),hypersensitive C-reactive protein(hs-CRP)]levels,the oxidative stress indexes[serum superoxide dismutase(SOD),malondialdehyde,glutathione peroxidase(GSH-Px)]levels,and the incidence of adverse reactions were compared between the two groups.Results:The total effective rate of the observation group was 91.67%,which was higher than 75.00%of the control group,and the difference was statistically significant(P<0.05).After the treatment,the NIHSS score,the levels of BNP,NSE,S100β protein,IL-6,TNF-α,hs-CRP,and MDA level in the observation group were lower than those in the control group;the upper limb FMA score,the lower limb FMA score,the BI score and the serum SOD and GSH-Px levels were higher than those in the control group;and the differences were statistically significant(P<0.05).During the treatment,there were no obvious adverse reactions in the two groups.Conclusions:On the basis of the routine treatment,rTMS treatment can improve the total effective rate,the FMA scores and the BI scores,improve the levels of oxidative stress indexes,and reduce the NIHSS scores,the serum neurological function index and serum inflammatory factor levels in the patients with hemiplegia after cerebral infarction.Moreover,it is superior to single routine treatment.
Cerebral infarctionHemiplegiaRepetitive transcranial magnetic stimulationOxidative stressFMA scoreBI score
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