Effects of compound Glycyrrhizin capsules combined with Mometasone furoate cream in treatment of Eczema
Objective:To observe effects of compound Glycyrrhizin capsules combined with Mometasone furoate cream in treatment of Eczema.Methods:A prospective study was conducted on 80 patients with eczema admitted to the hospital from October 2020 to August 2023.According to the random number table method,they were divided into observation group and control group,40 cases in each group.The control group was treated with Mometasone furoate cream for external use,while the observation group was treated with compound Glycyrrhizin capsules on the basis of that of the control group.The clinical efficacy,the skin lesions[eczema area and severity index(EASI)]and the pruritus scores before and after the treatment,the incidence of adverse reactions,and the recurrence rate were compared between the two groups.Results:The total effective rate of the observation group was 90.00%(36/40),which was higher than 72.50%(29/40)of the control group,and the difference was statistically significant(P<0.05).After the treatment,the scores of EASI and pruritus in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).After 6 months of follow-up,the recurrence rate of the observation group was 5.00%(2/40),which was lower than 20.00%(8/40)of the control group,and the difference was statistically significant(P<0.05).Conclusions:Compound Glycyrrhizin capsules combined with Mometasone furoate cream is effective in the treatment of eczema,which can accelerate the regression of skin lesions,reduce the pruritus degree,and reduce the recurrence rate.Moreover,it is superior to single Mometasone furoate cream treatment.
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