首页|硬膜外麻醉联合全身麻醉在乳腺癌根治术患者中的应用效果

硬膜外麻醉联合全身麻醉在乳腺癌根治术患者中的应用效果

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目的:观察硬膜外麻醉联合全身麻醉在乳腺癌根治术患者中的应用效果.方法:选取 2019 年 9 月至 2021 年 9 月该院收治的 136 例乳腺癌根治术患者进行前瞻性研究,按随机数字表法将其分为对照组与研究组各 68 例.对照组采用全身麻醉,研究组在对照组基础上联合硬膜外麻醉.比较两组不同时间[麻醉诱导前(T0)、诱导后即刻(T1)、插管后即刻(T2)、插管后5 min(T3)、拔管时(T4)、拔管后 5 min(T5)]血流动力学指标[平均动脉压(MAP)、心率]水平、麻醉恢复时间和不良反应发生率.结果:T1~T5 时,研究组MAP水平均低于对照组,T1 时,研究组心率水平高于对照组,T2~T5 时,研究组心率水平均低于对照组,差异均有统计学意义(P<0.05);研究组自主呼吸时间、意识恢复时间、拔管时间均短于对照组,差异有统计学意义(P<0.05);研究组麻醉不良反应发生率为8.82%(6/68),低于对照组的 22.06%(15/68),差异有统计学意义(P<0.05).结论:硬膜外麻醉联合全身麻醉应用于乳腺癌根治术患者中可改善血流动力学指标水平,缩短麻醉恢复时间,降低不良反应发生率,其效果优于单纯全身麻醉.
Application effects of epidural anesthesia combined with general anesthesia in patients undergoing radical mastectomy
Objective:To observe application effects of epidural anesthesia combined with general anesthesia in patients undergoing radical mastectomy.Methods:A prospective study was conducted on 136 patients undergoing radical mastectomy in the hospital from September 2019 to September 2021.According to the random number table method,they were divided into control group and study group,68 cases in each group.The control group was treated with general anesthesia,while the study group was combined with epidural anesthesia on the basis of that of the control group.The hemodynamic indexes[mean arterial pressure(MAP),heart rate]levels at different time[before anesthesia induction(T0),immediately after induction(T1),immediately after intubation(T2),5 min after intubation(T3),extubation(T4),5 min after extubation(T5)],the anesthesia recovery time,and the incidence of adverse reactions were compared between the two groups.Results:At T1-T5,the MAP level of the study group was lower than that of the control group;at T1,and the heart rate of the study group was higher than that of the control group;at T2-T5,the heart rate of the study group was lower than that of the control group;and the differences were statistically significant(P<0.05).The spontaneous breathing time,the consciousness recovery time and the extubation time of the study group were shorter than those of the control group,and the differences were statistically significant(P<0.05).Further,the incidence of adverse reactions to anesthesia in the study group was 8.82%(6/68),which was lower than 22.06%(15/68)in the control group,and the difference was statistically significant(P<0.05).Conclusions:Epidural anesthesia combined with general anesthesia can improve the levels of hemodynamic indexes,shorten the anesthesia recovery time and reduce the incidence of adverse reactions in the patients undergoing radical mastectomy.Moreover,it is superior to single general anesthesia.

Epidural anesthesiaGeneral anesthesiaRadical mastectomyHemodynamicsAdverse reaction

马传萍、赵卉

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邓州市中心医院麻醉科,河南 南阳 474150

硬膜外麻醉 全身麻醉 乳腺癌根治术 血流动力学 不良反应

2024

中国民康医学
中国社会工作协会

中国民康医学

影响因子:0.649
ISSN:1672-0369
年,卷(期):2024.36(10)
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