Application effects of epidural anesthesia combined with general anesthesia in patients undergoing radical mastectomy
Objective:To observe application effects of epidural anesthesia combined with general anesthesia in patients undergoing radical mastectomy.Methods:A prospective study was conducted on 136 patients undergoing radical mastectomy in the hospital from September 2019 to September 2021.According to the random number table method,they were divided into control group and study group,68 cases in each group.The control group was treated with general anesthesia,while the study group was combined with epidural anesthesia on the basis of that of the control group.The hemodynamic indexes[mean arterial pressure(MAP),heart rate]levels at different time[before anesthesia induction(T0),immediately after induction(T1),immediately after intubation(T2),5 min after intubation(T3),extubation(T4),5 min after extubation(T5)],the anesthesia recovery time,and the incidence of adverse reactions were compared between the two groups.Results:At T1-T5,the MAP level of the study group was lower than that of the control group;at T1,and the heart rate of the study group was higher than that of the control group;at T2-T5,the heart rate of the study group was lower than that of the control group;and the differences were statistically significant(P<0.05).The spontaneous breathing time,the consciousness recovery time and the extubation time of the study group were shorter than those of the control group,and the differences were statistically significant(P<0.05).Further,the incidence of adverse reactions to anesthesia in the study group was 8.82%(6/68),which was lower than 22.06%(15/68)in the control group,and the difference was statistically significant(P<0.05).Conclusions:Epidural anesthesia combined with general anesthesia can improve the levels of hemodynamic indexes,shorten the anesthesia recovery time and reduce the incidence of adverse reactions in the patients undergoing radical mastectomy.Moreover,it is superior to single general anesthesia.