NT-proBNP levels in prognosis evaluation of patients with acute myocardial infarction
Objective:To observe efficiency of combined detection of serum D-dimer,troponin I(cTnI)and N-terminal pro-brain natriuretic peptide(NT-proBNP)levels in prognosis evaluation of patients with acute myocardial infarction(AMI).Methods:A cross-sectional study was conducted on 110 patients with AMI admitted to the hospital from September 2020 to October 2021,and they were set as the observation group.According to different prognosis,they were divided into 71 patients with good prognosis and 39 patients with poor prognosis.In addition,110 healthy people who underwent physical examination in the hospital during the same period were selected as the control group.The levels of D-D,cTnI and NT-proBNP were compared between the two groups and among the AMI patients with different prognosis.The receiver operating characteristic(ROC)curve was drawn to analyze the efficiencies of single and combined detection of D-D,cTnI and NT-proBNP levels in the prognosis evaluation of the AMI patients.Results:The levels of D-D,cTnI and NT-proBNP in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).The levels of D-D,cTnI and NT-proBNP in the patients with poor prognosis were higher than those in the patients with good prognosis,and the differences were statistically significant(P<0.05).The ROC curve analysis showed that the area under the curve of single and combined detection of D-D,cTnI and NT-proBNP levels in the evaluation of the prognosis of the AMI patients were 0.690,0.729,0.698 and 0.952,respectively,and the efficiency of combined detection was higher than that of single detection.Conclusions:The efficiency of combined detection of D-D,cTnI and NT-proBNP levels in the prognosis evaluation of the AMI patients is higher than that of the single detection.
NETL
NSTL
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