Correlations among serum Hcy,hs-CRP,D-D levels and severity of patients with hypertensive disorder complicating pregnancy
Objective:To analyze correlations among serum homocysteine(Hcy),high-sensitivity C-reactive protein(hs-CRP),D-dimer(D-D)levels and severity of patients with hypertensive disorder complicating pregnancy.Methods:The clinical data of 98 patients with hypertensive disorder complicating pregnancy admitted to Shangqiu Renhe Hospital of Traditional Chinese Medicine from March 2022 to March 2023 were retrospectively analyzed and they were set as the observation group;and 91 healthy pregnant women who underwent routine prenatal examination during the same period were selected as the control group.The levels of serum Hcy,hs-CRP and D-D were compared between the two groups.According to the severity of the disease,they were divided into 54 cases of gestational hypertension group,24 cases of preeclampsia group and 20 cases of eclampsia group.The levels of serum Hcy,hs-CRP and D-D in the patients with hypertensive disorder complicating pregnancy of different severity were compared.The correlations among the levels of serum Hcy,hs-CRP and D-D and the severity of hypertensive disorder complicating pregnancy were analyzed.Results:The levels of serum Hcy,hs-CRP and D-D in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).The comparison of the levels of serum Hcy,hs-CRP and D-D showed that:gestational hypertension group<preeclampsia group<eclampsia group,and the differences were statistically significant(P<0.05).Pearson correlation analysis showed that the serum Hcy,hs-CRP and D-D levels were positively correlated with the severity of hypertensive disorder complicating pregnancy(r>0,P<0.05).Conclusions:The serum Hcy,hs-CRP and D-D levels are positively correlated with the severity of hypertensive disorder complicating pregnancy.
Hypertensive disorder complicating pregnancySerum homocysteineHigh-sensitivity C-reactive proteinD-dimerSeverity of diseaseCorrelation
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NSTL
万方数据
