Application effects of anterior quadratus lumborum block at the lateral supra-arcuate ligament combined with general anesthesia in laparoscopic cholecystectomy
Objective:To observe application effect of anterior quadratus lumborum block at the lateral supra-arcuate ligament(SA-AQLB)combined with general anesthesia in laparoscopic cholecystectomy(LC).Methods:A prospective study was conducted on 78 patients with LC admitted to the hospital from April 2020 to January 2022.According to the random number table method,they were divided into study group and control group,39 cases in each group.The control group was given general anesthesia,while the study group was combined with SA-AQLB on the basis of that of the control group.The tracheal extubation time,the remedial analgesia rate 48h after the surgery,the visual analogue scale(VAS)score at different time after the surgery(2,6,12,24,48 h after the surgery),the postoperative recovery(recovery time,first exhaust time,first out-of-bed time after,hospitalization time),the stress response index(random blood glucose,serum cortisol,serum epinephrine)levels,and the incidence of adverse reactions were compared between the two groups.Results:The remedial analgesia rate 48 h after the surgery in the study group was lower than that in the control group;the tracheal extubation time,the recovery time,the first exhaust time,the first out-of-bed time and the hospitalization time were shorter than those in the control group;and the differences were statistically significant(P<0.05).2,6,12,24 and 48 h after the surgery,the VAS scores of the study group were lower than those of the control group,and the differences were statistically significant(P<0.05).1 and 3 days after the surgery,the levels of random blood glucose,serum cortisol and serum adrenaline in the two groups were higher than those before operation,but those in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).However,there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions:SA-AQLB combined with general anesthesia in the LC patients can reduce the VAS scores,the remedial analgesia rate 48h after the surgery,the levels of stress response indexes,and shorten the tracheal extubation time,the recovery time,the first exhaust time,the first out-of-bed time and the hospitalization time.Moreover,it is superior to single general anesthesia.
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