Effects of hyperbaric oxygen combined with rehabilitation training on postoperative recovery of patients with aneurysmal subarachnoid hemorrhage
Objective:To investigate effects of hyperbaric oxygen combined with rehabilitation training on postoperative recovery of patients with aneurysmal subarachnoid hemorrhage(aSAH).Methods:A prospective study was conducted on 80 patients with aSAH admitted to this hospital from September 2019 to September 2022.According to the random number table method,they were divided into observation group and control group,40 cases in each group.The control group received routine rehabilitation training,while the observation group received the hyperbaric oxygen therapy on the basis of that of the control group.The levels of oxidative stress indexes[superoxide dismutase(SOD),total antioxidant capacity(T-AOC),advanced oxidation protein product(AOPP),malondialdehyde(MDA)],the National Institutes of Health stroke scale(NIHSS)score,the Barthel index(BI)score,and the Glasgow outcome scale(GOS)score were compared between the two groups before and after the intervention.Results:After the intervention,the levels of serum SOD,T-AOC and BI,GOS scores in the observation group were higher than those in the control group,the levels of MDA,AOPP and NIHSS scores were lower than those in the control group,and the differences were statistically significant(P<0.05).Conclusions:Hyperbaric oxygen combined with rehabilitation training is effective in the patients with aSAH,which can inhibit the oxidative stress,reduce the degree of neurological deficit,improve the self-care ability and improve the prognosis.Moreover,it is superior to single rehabilitation training.
AneurysmsSubarachnoid hemorrhageHyperbaric oxygenRehabilitation trainingNeurological functionActivity of daily living