Effects of Xuesaitong injection combined with conventional drugs in treatment of patients with acute cerebral infarction
Objective:To observe effects of Xuesaitong injection combined with conventional drugs in treatment of patients with acute cerebral infarction.Methods:The clinical data of 80 patients with acute cerebral infarction admitted to this hospital from February 2020 to February 2021 were retrospectively analyzed.According to different treatment methods,they were divided into control group and study group,40 cases in each group.The control group was treated with conventional drugs(Edaravone+Betahistine),while the study group was treated with Xuesaitong injection on the basis of that of the control group.Both groups were treated for 14 d.The clinical efficacy,the neurological deficit[National Institutes of Health stroke scale(NIHSS)]score,the vertebrobasilar artery(left vertebral artery,right vertebral artery,basilar artery)blood flow velocities,the inflammatory index[interleukin-1β(IL-1β),tumor necrosis factor-α(TNF-α)]levels,the cognitive function[Montreal Cognitive Assessment Scale(MoCA)]score,and the activities of daily living[Barthel Index(BI)]score were compared between the two groups before and after the treatment.Results:The total effective rate of the study group was 92.50%(37/40),which was higher than 75.00%(30/40)of the control group,and the difference was statistically significant(P<0.05).After the treatment,the NIHSS score of the study group was lower than that of the control group,and the difference was statistically significant(P<0.05).After the treatment,the blood flow velocities of left vertebral artery,right vertebral artery and basilar artery in the study group were higher than that in the control group,and the differences were statistically significant(P<0.05).After the treatment,the levels of IL-1β and TNF-α in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).Further,after the treatment,the scores of MoCA and BI in the study group were higher than those in the control group,and the differences were statistically significant(P<0.05).Conclusions:Xuesaitong injection combined with conventional drugs in the treatment of the patients with acute cerebral infarction can improve the total effective rate,the cognitive function and the activity of daily living scores,reduce the neurological deficit scores and inflammatory index levels,and improve the blood flow velocity of vertebrobasilar artery.Moreover,it is superior to single conventional drug therapy.
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