Effects of Qingfei Xiaoyong decoction combined with fibroscopic alveolar lavage in treatment of pulmonary abscess
Objective:To observe effects of Qingfei Xiaoyong decoction combined with fibroscopic alveolar lavage in treatment of pulmonary abscess.Methods:The clinical data of 86 patients with pulmonary abscess in this hospital from April 2021 to April 2023 were retrospectively analyzed.According to different treatment methods,they were divided into control group and study group,43 cases in each group.The control group was treated with fibroscopic alveolar lavage,while the study group was treated with Qingfei Xiaoyong decoction on the basis of that of the control group.The clinical efficacy,the TCM syndrome scores before and after the treatment,the blood gas analysis indexes[arterial partial pressure of oxygen(PaO2),blood oxygen saturation(SaO2),oxygenation index(PaO2/FiO2)]levels,the inflammatory factors[monocyte chemoattractant protein-1(MCP-1),tumor necrosis factor-α(TNF-α),pulmonary surfactant protein A(SPA),high mobility protein 1(HMGB1)]levels,and the incidence of adverse reactions were compared between the two groups.Results:The total effective rate of treatment in the study group was 95.35%(41/43),which was higher than 79.07%(34/43)in the control group,and the difference was statistically significant(P<0.05).After the treatment,the scores of TCM syndromes such as cough,turbid phlegm,chest pain and high fever in the two groups were lower than those before the treatment,those in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).The levels of PaO2,SaO2 and PaO2/FiO2 in the two groups were higher than those before the treatment,those in the study group were higher than those in the control group,and the differences were statistically significant(P<0.05).The levels of MCP-1,TNF-α,SPA and HMGB1 in the two groups were lower than those before the treatment,those in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).However,there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions:Qingfei Xiaoyong decoction combined with fibroscopic alveolar lavage in the treatment of the patients with pulmonary abscess can improve the clinical efficacy,reduce the TCM syndrome scores,improve the levels of blood gas analysis indexes,and reduce the body's inflammatory response.Moreover,it is superior to single fibroscopic alveolar lavage treatment.
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