Influencing factors of postoperative delirium in patients with Stanford type A aortic dissection
Objective:To analyze influencing factors of postoperative delirium in patients with Stanford type A aortic dissection(ATAD).Methods:The clinical data of 176 patients with ATAD admitted to the hospital from January 2020 to December 2023 were retrospectively analyzed.All patients received Sun's surgery.The incidence of delirium within 1 week after the surgery was statistically analyzed.Univariate and multivariate Logistic regression analysis were performed on the related factors of postoperative delirium.Results:Among the 176 patients with ATAD,39 patients(22.16%)had postoperative delirium within 1 week after the surgery,which was recorded as the occurrence group,and 137 patients(77.84%)did not have postoperative delirium,which was recorded as the non-occurrence group.The proportions of the patients with drinking history,intraoperative hypotension,intraoperative hyperglycemia,postoperative hematocrit(Hct)<30%,postoperative intravenous analgesia,postoperative infection,myocardial infarction and cerebral infarction in the occurrence group were higher than those in the non-occurrence group,the postoperative oxygenation index was lower than that in the non-occurrence group,the deep hypothermic circulatory arrest time and cardiopulmonary bypass time were longer than those in the non-occurrence group,and the differences were statistically significant(P<0.05).Logistic regression analysis showed that drinking history,intraoperative hypotension,intraoperative hyperglycemia,long deep hypothermic circulatory arrest time,long extracorporeal circulation time,low postoperative oxygenation index,postoperative Hct<30%,postoperative intravenous analgesia,postoperative infection,hypothermia,myocardial infarction and cerebral infarction were independent risk factors for postoperative delirium(OR>1,P<0.05).Conclusions:The incidence of postoperative delirium in the patients with ATAD is high.Drinking history,intraoperative hypotension,intraoperative hyperglycemia,long time of deep hypothermic circulatory arrest,long extracorporeal circulation time,low postoperative oxygenation index,postoperative Hct<30%,postoperative intravenous analgesia,postoperative infection,hypothermia,myocardial infarction and cerebral infarction were all the independent risk factors for postoperative delirium.
Stanford type AAortic dissectionSun's surgeryPostoperative deliriumInfluencing factor