Distribution and drug resistance of pathogenic bacteria in patients with nosocomial infection after interventional therapy of coronary heart disease
Objective:To analyze distribution and drug resistance of pathogenic bacteria in patients with nosocomial infection after interventional therapy of coronary heart disease.Methods:A prospective study was conducted on 600 patients with coronary heart disease undergoing interventional therapy admitted to this hospital from May 2020 to May 2023.The incidence of nosocomial infection in these patients with coronary heart disease undergoing interventional therapy was statistically analyzed.The secretions of the infected site were collected,and the distribution and drug resistance of pathogenic bacteria were analyzed.Results:In the 600 patients with interventional therapy of coronary heart disease,51 cases of nosocomial infection occurred,and the incidence of nosocomial infection was 8.5%(51/600).The infection sites included respiratory tract(41.18%),urinary system(25.49%),puncture site(13.73%),gastrointestinal tract(11.76%),skin tissue(3.92%)and so on.79 strains of pathogenic bacteria were detected in the secretions of the 51 patients with nosocomial infection,including 41 strains of Gram-positive bacilli(51.90%),among which the detection rate of Staphylococcus aureus was the highest(34.18%);and there were 38 strains(48.10%)of Gram-negative bacilli,and the detection rate of Escherichia coli was the highest(29.11%).The resistance of Staphylococcus aureus to Penicillin was more than 90%,and the resistance to Erythromycin was more than 70%.The resistance of Escherichia coli to Clindamycin was 100.00%,the resistance to Erythromycin was more than 80%,and the resistance to Penicillin was more than 70%.Conclusions:Staphylococcus aureus and Escherichia coli are common pathogens in the patients with nosocomial infection after interventional therapy for coronary heart disease,and their drug resistance is high.
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