Effects of Betahistine combined with Epley otolith repositioning in the treatment of benign paroxysmal positional vertigo
Objective:To observe effects of Betahistine combined with Epley otolith repositioning in the treatment of benign paroxysmal positional vertigo(BPPV).Methods:A prospective study was conducted on 230 patients with BPPV admitted to the hospital from October 2021 to March 2023.According to the random number table method,they were divided into observation group and control group,115 cases in each group.The control group was treated with Epley otolith repositioning method,while the observation group was treated with Betahistine mesylate tablets on the basis of that of the control group.The clinical efficacy,the degree of symptoms before and after the treatment[dizziness assessment rating scale(DARS),vestibular symptom index(VSI)],the quality of life[dizziness handicap inventory(DHI)],and the incidence of adverse reactions were compared between the two groups.Results:The total effective rate of the observation group was 94.78%(109/115),which was higher than 86.96%(100/115)of the control group,and the difference was statistically significant(P<0.05).After the treatment,the scores of DARS,VSI and DHI in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).However,there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions:Betahistine combined with Epley otolith repositioning method is effective in the treatment of the BPPV patients,which can accelerate the relief of vertigo and vestibular symptoms and improve the quality of life.Moreover,it is superior to single Epley otolith repositioning treatment.
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