Effects of Anerning granules combined with Cefixime in treatment of children with bacterial upper respiratory tract infection
Objective:To observe effects of Anerning granules combined with Cefixime in treatment of children with bacterial upper respiratory tract infection.Methods:The clinical data of 60 children with bacterial upper respiratory tract infection admitted to this hospital from September 2020 to September 2023 were retrospectively analyzed.According to the different treatment methods,they were divided into observation group and control group,30 cases in each group.The control group was treated with Cefixime,while the observation group was treated with Anerning granules on the basis of that of the control group.The clinical efficacy,the disappearance time of clinical symptoms,the levels of serum inflammatory factors[interleukin-8(IL-8),tumor necrosis factor-α(TNF-α),intercellular adhesion molecule-1(ICAM-1)],and the incidence of adverse reactions were compared between the two groups.Results:The total effective rate of the observation group was 93.33%,which was significantly higher than 60.00%of the control group,and the difference was statistically significant(P＜0.05).The disappearance time of clinical symptoms such as runny nose,sore throat,fever and cough in the observation group was shorter than that in the control group,and the difference was statistically significant(P＜0.05).After 5 days of treatment,the levels of serum inflammatory factors such as ICAM-1,TNF-α and IL-8 in the two groups were lower than those before the treatment,those in the observation group were lower than those in the control group,and the differences were statistically significant(P＜0.05).However,there was no significant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusions:Anerning granules combined with Cefixime in the treatment of the children with bacterial upper respiratory tract infection can improve the total effective rate of treatment,shorten the disappearance time of clinical symptoms,and reduce the levels of serum inflammatory factors.Moreover,it is superior to simple Cefixime treatment.
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