Effects of anatomical segmentectomy under video-assisted thoracoscope in treatment of patients with stage ⅠA non-small cell lung cancer
Objective:To observe effects of anatomical segmentectomy under video-assisted thoracoscope(VATS)in treatment of patients with stage ⅠA non-small cell lung cancer(NSCLC).Methods:A prospective study was conducted on 110 patients with stage ⅠA NSCLC admitted to our hospital from March 2021 to March 2023.According to the random number table method,they were divided into control group and study group,55 cases in each group.The control group underwent VATS lobectomy,while the study group underwent anatomical segmentectomy under VATS.The levels of perioperative indexes,pulmonary function indexes[forced vital capacity(FVC),forced expiratory volume in one second(FEV1),FEV1/FVC]and inflammatory indexes[interleukin-1β(IL-1β),interleukin-6(IL-6),C-reactive protein(CRP)]before and after the surgery,and the incidence of complications within 1 month after the surgery were compared between the two groups.Results:The operation time of the study group was longer than that of the control group,the intraoperative blood loss was less than that of the control group,the drainage time and the hospitalization time were shorter than those of the control group,and the differences were statistically significant(P<0.05).After the surgery,the levels of FVC,FEV1 and FEV1/FVC in the two groups were lower than those before the surgery,but those in the study group were higher than those in the control group,and the differences were statistically significant(P<0.05).After the surgery,the levels of IL-1β,IL-6 and CRP in the two groups were higher than those before the surgery,but those in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).However,there was no significant difference in the incidence of postoperative complications between the two groups(P>0.05).Conclusions:VATS anatomical segmentectomy for the stage ⅠA NSCLC patients can reduce the damage of lung function and the intraoperative blood loss,shorten the drainage time and the hospitalization time,and reduce the levels of inflammatory indexes.Moreover,it is superior to VATS lobectomy,but the operation time needs to be prolonged.
万方数据
维普
