Effects of minimally invasive transforaminal lumbar interbody fusion in treatment of elderly patients with degenerative lumbar spinal stenosis
Objective:To observe effects of minimally invasive transforaminal lumbar interbody fusion(MIS-TLIF)in treatment of elderly patients with degenerative lumbar spinal stenosis(DLSS).Methods:The clinical data of 67 elderly patients with DLSS admitted to the hospital from October 2019 to January 2022 were retrospectively analyzed.According to different surgical methods,they were divided into observation group(n=35)and control group(n=32).The observation group was treated with MIS-TLIF,while the control group was treated with open transforaminal fusion(O-TLIF).The levels of operation-related indicators(operation time,first out-of-bed time after the surgery,postoperative hospitalization time,number of intraoperative fluoroscopy,intraoperative blood loss,and drainage volume),the levels of inflammatory factors[C-reactive protein(CRP),procalcitonin(PCT),interleukin-6(IL-6)]and the imaging parameters(Cobb angle of injured vertebrae,lumbar lordosis angle)before and after the surgery,and the incidence of complications were compared between the two group.Results:The operation time of the observation group was longer than that of the control group,the first out-of-bed time after the surgery and the hospitalization time were shorter than those of the control group,the number of intraoperative fluoroscopy was more than that of the control group,the intraoperative blood loss and drainage volume were less than those of the control group,and the differences were statistically significant(P<0.05).1 day after the surgery,the levels of serum IL-6,PCT and CRP in the two groups were higher than those before the surgery,but those in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).6 months after the surgery,the lumbar lordosis angle of the two groups were larger than those before the surgery,and the Cobb angle of the injured vertebrae were smaller than those before the surgery,but there were no significant differences between the two groups(P>0.05).There was no significant difference in the incidence of postoperative complications between the two groups(P>0.05).Conclusions:MIS-TLIF in the treatment of the DLSS patients can shorten the first out-of-bed time and the postoperative hospitalization time,reduce the intraoperative blood loss and the drainage volume,and reduce the levels of inflammatory factors.Moreover,it is superior to O-TLIF,but it is necessary to prolong the operation time and increase the number of intraoperative fluoroscopy.
万方数据
维普
