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血栓通联合阿司匹林治疗急性脑梗死患者的效果

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目的:观察血栓通联合阿司匹林治疗急性脑梗死(ACI)患者的效果.方法:选取 2022 年 1 月至 2023 年 12 月该院收治的70 例ACI患者进行前瞻性研究,以随机数字表法将其分为对照组和观察组各 35 例.对照组给予阿司匹林治疗,观察组在对照组基础上联合血栓通治疗,比较两组治疗前后中医证候积分、神经功能缺损[美国国立卫生研究院卒中量表(NIHSS)]评分、炎性因子[白细胞介素-6(IL-6)、超敏C反应蛋白(hs-CRP)]水平和血液流变学指标[血浆纤维蛋白原(FIB)、血浆黏度(PV)、全血高切黏度(HBV)]水平.结果:治疗后,两组中医证候积分和NIHSS评分均低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05);治疗后,两组IL-6、hs-CRP、FIB、PV和HBV水平均低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05).结论:血栓通联合阿司匹林治疗ACI患者可降低中医证候积分、NIHSS评分、炎性因子水平和血液流变学指标水平,效果优于单纯阿司匹林治疗.
Effects of Xueshuantong combined with Aspirin in treatment of patients with acute cerebral infarction
Objective:To observe effects of Xueshuantong combined with Aspirin in treatment of patients with acute cerebral infarction(ACI).Methods:A prospective study was conducted on 70 patients with ACI admitted to the hospital from January 2022 to December 2023.They were divided into control group and observation group by using the random number table method,35 cases in each group.The control group was treated with Aspirin,while the observation group was treated with Xueshuantong on the basis of that of the control group.The scores of TCM syndromes,the neurological deficits[National Institutes of Health stroke scale(NIHSS)]score,and the levels of inflammatory factors[interleukin-6(IL-6),high-sensitivity C-reactive protein(hs-CRP)]and hemorheological indexes[plasma fibrinogen(FIB),plasma viscosity(PV),whole blood high shear viscosity(HBV)]were compared between the two groups before and after the treatment.Results:After the treatment,the scores of TCM syndromes and NIHSS in the two groups were lower than those before the treatment,those in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).Further,after the treatment,the levels of IL-6,hs-CRP,FIB,PV and HBV in the two groups were lower than those before the treatment,those in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).Conclusions:Xueshuantong combined with Aspirin in the treatment of the ACI patients can reduce the TCM syndrome scores,the NIHSS scores,the inflammatory factor levels and the hemorheology index levels.Moreover,it is superior to simple Aspirin treatment.

Acute cerebral infarctionAspirinXueshuantongTCM syndrome scoreNeurological deficitInflammatory factorHemorheology

沈强群、李忠阳

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湖口县中医医院药剂科,江西 九江 332500

急性脑梗死 阿司匹林 血栓通 中医证候积分 神经功能缺损 炎性因子 血液流变学

2024

中国民康医学
中国社会工作协会

中国民康医学

影响因子:0.649
ISSN:1672-0369
年,卷(期):2024.36(15)