Comparison of application effects of Ciprofol and Propofol anesthesia in laparoscopic cholecystectomy in elderly patients
Objective:To compare application effects of Ciprofol and Propofol anesthesia in laparoscopic cholecystectomy in elderly patients.Methods:A prospective study was conducted on 80 elderly patients who underwent laparoscopic cholecystectomy in this hospital from June to December 2023.According to the random number table method,they were divided into observation group and control group,40 cases in each group.The observation group was induced and maintained by Ciprofol anesthesia,while the control group was induced and maintained by Propofol anesthesia.The levels of anesthesia-related indicators(anesthesia induction time,anesthesia recovery time,and time to leave the anesthesia recovery room),the hemodynamic indicators(heart rate,central venous pressure,and blood oxygen saturation)levels at different times[before anesthesia induction(T0),3 min after induction(T1),at the time of entering endoscope(T2),and at the end of surgery(T3)],the sedation(Ramsay score)scores at different times(10,30 min before surgery and at the end of surgery),and the incidence of adverse reactions were compared between the two groups.Results:There were no significant differences in the anesthesia recovery time and the time to leave the anesthesia recovery room between the two groups(P>0.05).The anesthesia induction time in the observation group was longer than that in the control group,and the difference was statistically significant(P<0.05).At T1,T2 and T3,the levels of heart rate,central venous pressure and blood oxygen saturation in the two groups were lower than those at T0,but those in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).There were no significant differences in the Ramsay scores between the two groups 10,30 min after the surgery and at the end of the surgery(P>0.05).There was no significant difference in the incidence of hypotension,nausea and vomiting between the two groups(P>0.05).The incidence of injection pain in the observation group was significantly lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusions:Ciprofol anesthesia in laparoscopic cholecystectomy in the elderly patients can stabilize the levels of hemodynamic indicators and reduce the incidence of injection pain.It is superior to Propofol anesthesia,but the anesthesia induction time needs to be prolonged.
万方数据
维普
