Influencing factors of recurrence after healing in patients with diabetic foot ulcer
Objective:To analyze influencing factors of recurrence after healing in patients with diabetic foot ulcer(DFU).Methods:A cross-sectional study was conducted on 178 patients with DFU admitted to the hospital from July 2020 to January 2023.The clinical data of these patients were collected.The levels of glycated hemoglobin(HbA1c)and albumin(ALB)were detected.They were followed up for 1 year.According to whether DFU recurred after healing,these patients were divided into recurrence group and non-recurrence group.Logistic regression was used to analyze the influencing factors of recurrence after healing in these patients with DFU.Results:Among the 178 DFU patients,64 cases recurred after healing,with a recurrence rate of 35.96%(64/178).There were no significant differences between the two groups in terms of gender,body mass index(BMI),drinking history,smoking history,marital status,combined hypertension,combined coronary heart disease,combined hyperlipidemia,diabetes course,education,combined diabetic retinopathy,combined diabetic nephropathy,number of ulcers,area of ulcers,and treatment methods(P>0.05).The proportions of the patients with age≥60 years old,Wagner grade 3-5,ulcer site at the foot sole,ankle brachial index<0.9,HbA1c≥7.5%,ALB<30 g/L,and moderate to severe infection at the ulcer site in the recurrence group were higher than those in the non-recurrence group,and the differences were statistically significant(P<0.05).Logistic regression analysis showed that the age≥60 years old,Wagner grade 3-5,ulcers at the foot sole,ankle brachial index<0.9,HbA1c≥7.5%,ALB<30 g/L,and moderate to severe infection at the ulcer site were risk factors for recurrence in the DFU patients after healing(OR>1,P<0.05).Conclusions:Age≥60 years old,Wagner grade 3-5,ulcers at the foot sole,ankle brachial index<0.9,HbA1c≥7.5%,ALB<30 g/L,and moderate to severe infection at the ulcer site are the risk factors for recurrence in the DFU patients after healing.
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