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急性白血病PICC患者发生导管相关性感染的影响因素

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目的:分析急性白血病经外周静脉穿刺中心静脉置管(PICC)患者发生导管相关性感染的影响因素.方法:回顾性分析2019 年 1 月至 2022 年 12 月该院收治的 89 例急性白血病患者的临床资料,均接受PICC,根据是否发生导管相关性感染将其分为发生组和未发生组,收集两组临床资料,分析急性白血病PICC患者发生导管相关性感染的影响因素.结果:89 例急性白血病PICC患者,共发生22 例导管相关性感染,发生率为 24.72%(22/89);两组年龄、合并糖尿病、化疗次数、穿刺次数、置管时间、导管滑脱、糖皮质激素使用史、免疫功能、换药间隔时间比较,差异均有统计学意义(P<0.05);两组性别、体质量指数、合并高血压、疾病类型、穿刺部位比较,差异均无统计学意义(P>0.05);Logistic回归分析结果显示,年龄≥60岁、合并糖尿病、化疗次数≥6次、穿刺次数≥3次、置管时间≥2 个月、发生导管滑脱、有糖皮质激素使用史、免疫功能低下、换药间隔时间≥8 d均为急性白血病PICC患者发生导管相关性感染的危险因素(OR>1,P<0.05).结论:年龄≥60 岁、合并糖尿病、化疗次数≥6 次、穿刺次数≥3 次、置管时间≥2 个月、发生导管滑脱、有糖皮质激素使用史、免疫功能低下、换药间隔时间≥8 d均为急性白血病PICC患者发生导管相关性感染的危险因素.
Influencing factors of catheter-related infection in acute leukemia patients with PICC
Objective:To analyze influencing factors of catheter-related infection in patients with acute leukemia undergoing peripherally inserted central venous catheter(PICC).Methods:The clinical data of 89 patients with acute leukemia admitted to the hospital from January 2019 to December 2022 were retrospectively analyzed.All patients received PICC.They were divided into occurrence group and non-occurrence group according to whether catheter-related infection occurred.The general data of two groups were collected.The influencing factors of catheter-related infection in the patients with acute leukemia undergoing PICC were analyzed.Results:Among the 89 patients with acute leukemia undergoing PICC,a total of 22 cases were infected with an incidence rate of 24.72%(22/89).There were significant differences between the two groups in age,combined diabetes,chemotherapy frequency,puncture frequency,catheter insertion time,catheter slippage,Glucocorticoid use history,immune function and dressing change interval(P<0.05).There were no statistically significant differences in gender,body mass index,combined hypertension,disease type,and puncture site between the two groups(P>0.05).Logistic regression analysis showed that age≥60 years old,combined diabetes,chemotherapy frequency≥6 times,puncture frequency≥3 times,catheterization time≥2 months,catheter slippage,Glucocorticoid use history,low immune function,and dressing change interval≥8 days were risk factors for catheter-related infection in the patients with acute leukemia undergoing PICC(OR>1,P<0.05).Conclusions:Age≥60 years old,combined diabetes,chemotherapy frequency≥6 times,puncture frequency≥3 times,catheterization time≥2 months,catheter slippage,Glucocorticoid use history,low immune function,and dressing change interval≥8 days are the risk factors for catheter-related infection in the patients with acute leukemia undergoing PICC.

Acute leukemiaPeripherally inserted central venous catheterCatheter-related infectionInfluencing factor

胡娟

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安阳地区医院血液一科,河南 安阳 455000

急性白血病 经外周静脉穿刺中心静脉置管 导管相关性感染 影响因素

2024

10.3969/j.issn.1672-0369.2024.16.003

中国民康医学
中国社会工作协会

中国民康医学

影响因子：0.649
ISSN：1672-0369
年,卷(期)：2024.36(16)
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