Influencing factors of postoperative cognitive dysfunction in patients undergoing laparoscopic cholecystectomy
Objective:To analyze influencing factors of postoperative cognitive dysfunction in patients undergoing laparoscopic cholecystectomy(LC).Methods:The clinical data of 80 patients with cholecystolithiasis who underwent LC in this hospital from June 2022 to June 2023 were retrospectively analyzed.These patients were followed up for 15 days after the surgery.According to whether postoperative cognitive dysfunction occurred,they were divided into the occurrence group and the non-occurrence group.The baseline data of the two groups were compared.Logistic regression was used to analyze the influencing factors of postoperative cognitive dysfunction in the LC patients.Results:Among the 80 patients with cholecystolithiasis who underwent LC,19 developed cognitive dysfunction after the surgery with an incidence rate of 23.75%(19/80).There were no statistically significant differences in gender,body mass index,combined hypertension,cholecystolithiasis hyperlipidemia,smoking history,and alcohol consumption history between the two groups(P>0.05).There were significant differences in age,operation time,pneumoperitoneum pressure,postoperative analgesia and diabetes between the two groups(P<0.05).Logistic regression analysis showed that age≥60 years,operation time≥60 minutes,pneumoperitoneum pressure≥11.2 mmHg,and combined diabetes were risk factors for postoperative cognitive dysfunction in the LC patients(OR>1,P<0.05),and postoperative analgesia was a protective factor for postoperative cognitive dysfunction in the LC patients(OR<1,P<0.05).Conclusions:Age≥60 years old,operation time≥60 min,pneumoperitoneum pressure≥11.2 mmHg and combined diabetes are the risk factors for postoperative cognitive dysfunction in the LC patients,and postoperative analgesia is the protective factor.
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