Effects of low-dose Methylprednisolone combined with Azithromycin in treatment of children with mycoplasma pneumonia
Objective:To observe effects of low-dose Methylprednisolone combined with Azithromycin in treatment of children with mycoplasma pneumonia.Methods:The clinical data of 80 children with mycoplasma pneumonia admitted to this hospital in 2023 were retrospectively analyzed.According to the treatment methods,they were divided into control group and observation group,40 cases in each group.The control group was treated with Azithromycin,while the observation group was treated with low-dose Methylprednisolone on the basis of that of the control group.The clinical efficacy,the disappearance time of clinical symptoms(fever,cough),hospitalization time,the levels of inflammatory factors[C-reactive protein(CRP),white blood cell count(WBC)],and the incidence of adverse reactions were compared between the two groups.Results:The total effective rate of the observation group was 97.50%(39/40),which was higher than 80.00%(32/40)of the control group,and the difference was statistically significant(P<0.05).The disappearance time of fever,cough and the hospitalization time in the observation group were shorter than those in the control group,and the differences were statistically significant(P<0.05).After the treatment,the levels of CRP and WBC in the two groups were lower than those before the treatment,those in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).However,there was no significant difference in the incidence of adverse reactions between the two groups(P<0.05).Conclusions:Low-dose Methylprednisolone combined with Azithromycin in the treatment of the children with mycoplasma pneumonia can improve the total effective rate of treatment,shorten the disappearance time of clinical symptoms and the hospitalization time,and reduce the levels of inflammatory indicators.Moreover,it is superior to simple Azithromycin treatment.
Small doseMethylprednisoloneAzithromycinMycoplasma pneumoniaInflammatory factorAdverse reaction
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