Efficiency of combined detection of fasting blood glucose,serum C-peptide and glycosylated hemoglobin levels in diagnosis of diabetic nephropathy
Objective:To analyze efficiency of combined detection of serum C-peptide,fasting blood glucose(FPG),and glycosylated hemoglobin(HbA1c)levels in diagnosis of diabetic nephropathy.Methods:A total of 50 patients with diabetic nephropathy admitted to this hospital from January 2022 to August 2023 were selected as the study group,and 50 healthy subjects during the same period were selected as the control group.The levels of serum C-peptide,FPG,and HbA1c were compared between the two groups.The receiver operating characteristic(ROC)curve was used to analyze the efficiencies of single and combined detection of serum C-peptide,FPG,and HbA1c levels in the diagnosis of diabetic nephropathy.Results:The levels of serum C-peptide,FPG,and HbA1c in the study group were higher than those in the control group,and the differences were statistically significant(P<0.05).The ROC curve analysis showed that the area under the curve of single and combined detection of serum C-peptide,FPG,and HbA1c levels in the diagnosis of diabetic nephropathy were 0886,0.825,0.801 and 0.912,respectively.The area under the curve of combined detection was higher than that of each single detection.Conclusions:The efficiency of combined detection of serum C-peptide,FPG,and HbA1c levels in the diagnosis of diabetic nephropathy is higher than that of each single detection.