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肝硬化患者门静脉血栓形成的影响因素

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目的:分析肝硬化患者门静脉血栓形成的影响因素.方法:选取 2018 年 11 月至 2023 年 11 月于南昌市第九医院就诊的116 例肝硬化患者进行横断面研究,根据影像学检查结果分为血栓组与非血栓组,收集两组临床资料,分析肝硬化患者门静脉血栓形成的影响因素.结果:116 例肝硬化患者中,40 例形成门静脉血栓,发生率为 34.48%(40/116);两组性别、年龄、肝硬化病因、吸烟史、合并高血压、体质量指数、Child-Pugh分级比较,差异均无统计学意义(P>0.05);两组合并糖尿病、D-二聚体(D-D)水平、C反应蛋白/白蛋白比值(CAR)、全身免疫炎症反应指数(SII)、门静脉宽度比较,差异均有统计学意义(P<0.05);Logistic回归分析结果显示,合并糖尿病、D-D≥2.5 mg/L、SII≥500×109/L、门静脉宽度≥15 mm均为肝硬化患者门静脉血栓形成的危险因素(P<0.05).结论:合并糖尿病、D-D≥2.5 mg/L、SII≥500×109/L、门静脉宽度≥15 mm均为肝硬化患者门静脉血栓形成的危险因素.
Influencing factors of portal vein thrombosis in patients with liver cirrhosis
Objective:To analyze influencing factors of portal vein thrombosis in patients with cirrhosis.Methods:A cross-sectional study was conducted on 116 patients with liver cirrhosis who were admitted to Nanchang Ninth Hospital from November 2018 to November 2023.According to the results of imaging examination,they were divided into thrombus group and non-thrombus group.The clinical data of the two groups were collected.The influencing factors of portal vein thrombosis in these patients with cirrhosis were analyzed.Results:Among the 116 patients with cirrhosis,40 cases suffered from portal vein thrombosis,and the incidence rate was 34.48%(40/116).There were no significant differences in gender,age,etiology of cirrhosis,smoking history,combined hypertension,body mass index and Child-Pugh classification between the two groups(P>0.05).There were significant differences in combined diabetes mellitus,D-dimer(D-D)level,C-reactive protein to albumin ratio(CAR),systemic immune inflammatory response index(SII)and portal vein width between the two groups(P<0.05).Logistic regression analysis showed that combined diabetes mellitus,D-D≥2.5 mg/L,SII≥500×109/L and portal vein width≥15 mm were risk factors for portal vein thrombosis in the patients with cirrhosis(P<0.05).Conclusions:Combined diabetes mellitus,D-D≥2.5 mg/L,SII≥500×109/L,and portal vein width≥15 mm are the risk factors for portal vein thrombosis in the patients with cirrhosis.

Liver cirrhosisPortal vein thrombosisDiabetesPortal vein widthInfluencing factor

李慧国、杨道坤

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南昌市第九医院消化内科,江西 南昌 330046

新乡医学院第一附属医院感染三科,河南 新乡 453199

肝硬化 门静脉血栓 糖尿病 门静脉宽度 影响因素

2024

中国民康医学
中国社会工作协会

中国民康医学

影响因子:0.649
ISSN:1672-0369
年,卷(期):2024.36(17)