Application effects of ultrasound-guided paravertebral nerve block combined with general anesthesia in patients undergoing laparoscopic cholecystectomy
Objective:To observe application effects of ultrasound-guided paravertebral nerve block(PVB)combined with general anesthesia in patients undergoing laparoscopic cholecystectomy(LC).Methods:The clinical data of 108 patients with LC admitted to this hospital from September 2020 to April 2023 were retrospectively analyzed.According to different anesthesia methods,they were divided into control group(n=54)and observation group(n=54).The control group was treated with general anesthesia,while the observation group was treated with ultrasound-guided PVB on this basis.The levels of hemodynamic indexes[oxygen saturation(SpO2),stroke volume variation(SVV),mean arterial pressure(MAP)]at different time[admission(T0),intubation(T1),skin incision(T2),extubation(T3)],the sedation degree(Ramsay sedation)score,the stress response indexes[cortisol(Cor),norepinephrine(NE)]levels before and after the surgery,and the incidence of adverse reactions of anesthesia were compared between the two groups.Results:At T1-T3,there was no significant difference in the SpO2 level between the two groups(P＞0.05).At T1-T3,the SVV level of the observation group was lower than that of the control group,the MAP level was higher than that of the control group,and the differences were statistically significant(P＜0.05).4,8,12,and 24 h after the surgery,there were no statistically significant differences in the Ramsay sedation score between the two groups(P＞0.05).6 h after the surgery,the levels of Cor and NE in the two groups were higher than those before anesthesia,but those in the observation group were lower than those in the control group,and the differences were statistically significant(P＜0.05).The incidence of adverse reactions of anesthesia in the observation group was lower than that in the control group,and the difference was statistically significant(P＜0.05).Conclusions:Ultrasound-guided PVB combined with general anesthesia in the LC patients can effectively reduce the surgical stress response,stabilize the hemodynamics and reduce the incidence of adverse reactions.Moreover,it is superior to simple general anesthesia.
万方数据
维普
