Effects of Eszopiclone combined with Escitalopram oxalate in treatment of post-stroke anxiety and depression patients with insomnia
Objective:To observe effects of Eszopiclone combined with Escitalopram oxalate in treatment of post-stroke anxiety and depression patients with insomnia.Methods:A prospective study was conducted on 120 patients with post-stroke anxiety and depression and insomnia admitted to the hospital from January 2022 to July 2023.According to the random number table method,they were divided into study group and control group,60 cases in each group.The control group was treated with Escitalopram oxalate,while the study group was treated with Eszopiclone on the basis of that of the control group.The total effective rate,the scores of Pittsburgh sleep quality index(PSQI),the generalized anxiety scale(GAD-7),the patient health questionnaire(PHQ-9),and the Montreal cognitive assessment scale(MoCA),and the incidence of adverse reactions were compared between the two groups.Results:The total effective rate of the study group was 91.67%,which was significantly higher than 73.33%of the control group,and the difference was statistically significant(P＜0.05).After the treatment,the MoCA scores of the two groups were higher than those before the treatment,and that in the study group was higher than that in the control group;the PSQI,GAD-7 and PHQ-9 scores of the two groups were lower than those before the treatment,and those in the study group were lower than those in the control group;and the differences were statistically significant(P＜0.05).However,there was no significant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusions:Escitalopram oxalate combined with Escitalopram oxalate in the treatment of post-stroke anxiety and depression with insomnia can improve the total effective rate of treatment and the MoCA score,and reduce the PSQI,GAD-7 and PHQ-9 scores.Moreover,it is superior to simple Escitalopram oxalate treatment.
万方数据
维普
