Comparison of effects of modified Chaihu Jia Longgu Muli decoction and Chaihu Shugan powder in treatment of patients with depression of liver qi stagnation type
Objective:To compare effects of modified Chaihu Jia Longgu Muli decoction and Chaihu Shugan powder in treatment of patients with depression of liver qi stagnation type.Methods:A prospective study was conducted on 120 patients with depression of liver qi stagnation type admitted to this hospital from January to May 2023.According to the random number table method,they were divided into observation group and control group,60 cases in each group.The control group was treated with Chaihu Shugan powder,while the observation group was treated with Chaihu Jia Longgu Muli decoction.The total effective rate of treatment,the self-rating depression scale(SDS)score,the Hamilton depression scale(HAMD)score,the Barthel index(BI)score,the total score of TCM syndromes,and the incidence of adverse reactions were compared between the two groups.Results:The total effective rate of the observation group was 96.67%,which was significantly higher than 80.00%of the control group,and the difference was statistically significant(P<0.05).After the treatment,the BI scores of the two groups were higher than those before the treatment,and that in the observation group was higher than that in the control group;the SDS and HAMD scores as well as the total scores of TCM syndromes in the two groups were lower than those before the treatment,and those in the observation group were lower than those in the control group;and the differences were statistically significant(P<0.05).However,there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions:Chaihu Jia Longgu Muli decoction can improve the total effective rate and the BI scores,and reduce the SDS scores,the HAMD scores and the total score of TCM syndromes in the treatment of the patients with depression of liver qi stagnation type.Moreover,it is superior to Chaihu Shugan powder treatment.