Distribution and drug resistance analysis of pathogenic bacteria in wound secretions of patients with traumatic infection
Objective:To analyze distribution and drug resistance analysis of pathogenic bacteria in wound secretions of patients with traumatic infection.Methods:The clinical data of 210 patients with traumatic infection admitted to the hospital from March 2020 to September 2022 were retrospectively analyzed.The wound secretions were collected for bacterial culture and drug sensitivity test.The distribution and drug resistance of the pathogenic bacteria in the wound secretions of the patients with traumatic infection were analyzed.Results:246 strains of pathogenic bacteria were detected in the wound secretion samples of the 210 patients with traumatic infection,including 147 strains of Gram-negative bacteria,78 strains of Gram-positive bacteria and 21 strains of fungi.Gram-negative bacteria were mainly Escherichia coli,Pseudomonas aeruginosa and Enterobacter cloacae.Gram-positive bacteria were mainly Staphylococcus aureus and coagulase-negative Staphylococcus.The resistance rate of Escherichia coli to Ampicillin was the highest(87.50%),and it was not resistant to Imipenem and Meropenem.The resistance rates of Pseudomonas aeruginosa to Compound sulfamethoxazole and Minocycline were the highest(both 100.00%),and the resistance rates to Levofloxacin,Ceftazidime,Cefepime,Imipenem and Meropenem were lower(all<15%).The resistance rate of Enterobacter cloacae to Ampicillin was the highest(100.00%),and it was not resistant to Cefoperazone,Imipenem and Meropenem.Staphylococcus aureus and coagulase-negative Staphylococcus had the highest resistance rate to Tetracycline(100.00%),and they were not resistant to Vancomycin,Teicoplanin and Linezolid.Conclusions:The distribution of pathogenic bacteria in the wound secretions of the patients with traumatic infection is mainly Gram-negative bacteria,among which Escherichia coli accounts for the highest proportion and has the highest resistance rate to Ampicillin.