Effects of Diyu Shengbai tablets combined with Methimazole in treatment of patients with hyperthyroidism complicated with leukopenia
Objective:To observe effects of Diyu Shengbai tablets combined with Methimazole in treatment of patients with hyperthyroidism complicated with leukopenia.Methods:A prospective study was conducted on 92 patients with hyperthyroidism and leukopenia admitted to Henan Hongli hospital from February 2022 to February 2023.According to the random number table method,they were divided into study group and control group,46 cases in each group.The control group was treated with Methimazole,while the study group was treated with Diyu Shengbai tablets on the basis of that of the control group.The clinical efficacy,the thyroid function indexes[thyroid stimulating hormone(TSH),free triiodothyronine(FT3)and free tetraiodothyronine(FT4)]levels and the white blood cell count before and after the treatment,and the incidence of adverse reactions were compared between the two groups.Results:The total effective rate of treatment in the study group was 89.13%(41/46),which was higher than 71.74%(33/46)in the control group,and the difference was statistically significant(P<0.05).After the treatment,the TSH level of the study group was higher than that of the control group,the levels of FT3 and FT4 were lower than those of the control group,and the differences were statistically significant(P<0.05).After the treatment,the white blood cell counts of the two groups were higher than those before the treatment,that in the study group was higher than that in the control group,and the differences were statistically significant(P<0.05).Further,the incidence of adverse reactions in the study group was 8.70%(4/46),which was lower than 23.91%(11/46)in the control group,and the difference was statistically significant(P<0.05).Conclusions:Diyu Shengbai tablets combined with Methimazole can improve the total effective rate and the white blood cell count,improve the levels of thyroid function indexes and reduce the incidence of adverse reactions in the treatment of hyperthyroidism complicated with leukopenia.Moreover,it is superior to simple Methimazole treatment.
万方数据
维普
