Predictive value of serum total IgE,eosinophils and coagulation function indexes levels in children with Henoch-Schonlein purpura complicated with Henoch-Schonlein purpura nephritis
Objective:To analyze predictive value of serum total immunoglobulin E(IgE),eosinophils and coagulation function indexes levels in children with Henoch-Schonlein purpura(HSP)complicated with Henoch-Schonlein purpura nephritis(HSPN).Methods:The clinical data of 96 children with HSP admitted to this hospital from January 2020 to January 2023 were retrospectively analyzed.According to the presence or absence of HSPN,they were divided into HSP group(n=65)and HSPN group(n=31).The levels of serum total IgE,eosinophils and coagulation function indexes[prothrombin time(PT),activated partial thromboplastin time(APTT)]were compared between the two groups.The receiver operating curve(ROC)was used to analyze their predictive value for HSPN in the children with HSP.Results:The levels of serum total IgE and eosinophils in HSPN group were higher than those in HSP group,the PT and APTT were shorter than those in HSP group,and the differences were statistically significant(P<0.05).The ROC curve analysis showed that the areas under the curve of the levels of serum total IgE,eosinophil level,PT and APTT in the prediction of HSPN in the children with HSP were 0.795,0.710,0.774 and 0.752,separately,all of which had certain predictive value.Conclusions:The serum total IgE,eosinophils and coagulation function indexes levels has certain predictive value for HSPN in the children with HSP.
Allergic purpuraAllergic purpura nephritisSerum total immunoglobulin EEosinophilCoagulation function
万方数据
维普
