Effects of Huatan Tongluo decoction combined with conventional Western medicine on patients with acute cerebral infarction
Objective:To observe effects of Huatan Tongluo decoction combined with conventional Western medicine in treatment of patients with acute cerebral infarction(ACI).Methods:A prospective study was conducted on 76 patients with ACI admitted to Linying County Hospital of traditional Chinese Medicine from March 2021 to March 2023.According to the random number table method,they were divided into observation group and control group,38 cases in each group.Both groups were given routine treatment.On this basis,the control group was treated with conventional Western medicine(Aspirin+Atorvastatin calcium),while the observation group was treated with Huatan Tongluo decoction on the basis of that of the control group.The clinical efficacy,the neurological deficit[National Institutes of Health stroke scale(NIHSS)]score,the daily living ability[Barthel index(BI)]score,the blood lipid indexes[total cholesterol(TC),low-density lipoprotein cholesterol(LDL-C),triglyceride(TG)]levels,the inflammatory factors[high-sensitivity C-reactive protein(hs-CRP),interleukin-6(IL-6)]levels before and after the treatment,and the incidence of adverse reactions were compared between the two groups.Results:The total effective rate of the observation group was 92.11%(35/38),which was higher than 73.68%(28/38)of the control group,and the difference was statistically significant(P<0.05).After the treatment,the NIHSS score of the observation group was lower than that of the control group,the BI score was higher than that of the control group,and the differences were statistically significant(P<0.05).After the treatment,the levels of TC,LDL-C,TG,IL-6 and hs-CRP in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).However,there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions:Huatan Tongluo decoction combined with conventional Western medicine can improve the total effective rate and the daily living ability scores of the ACI patients,and reduce the neurological deficit scores,the blood lipid indexes and inflammatory factor levels.Moreover,it is superior to simple conventional Western medicine treatment.
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