Effects of Fengsui dan and Fuzi Lizhong pills combined with conventional Western medicine in treatment of acne patients of intermingled cold and heat type
Objective:To observe effects of Fengsui dan and Fuzi Lizhong pills combined with conventional Western medicine in treatment of acne patients of intermingled cold and heat type.Methods:A prospective study was conducted on 100 patients with acne of intermingled cold and heat type admitted to this hospital from March to October 2023.According to the random number table method,they were divided into control group and study group,50 cases in each group.The control group was treated with conventional Western medicine,while the study group was treated with Fengsui dan combined with Fuzi Lizhong pills on the basis of that of the control group.The clinical efficacy,the skin lesion scores,the serological indexes[interleukin-1α(IL-1α),soluble interleukin-2 receptor(SIL-2R)]levels,and the quality of life[acne-specific quality of life scale(Acne-QOL)]score before and after the treatment,and the incidence of adverse reactions were compared between the two groups.Results:The total effective rate of treatment in the study group was 86.00%(43/50),which was higher than 62.00%(31/50)in the control group,and the difference was statistically significant(P<0.05).After the treatment,the skin lesion score of the study group was lower than that of the control group,and the difference was statistically significant(P<0.05).After the treatment,the levels of IL-1α and SIL-2R in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).After the treatment,the Acne-QOL score of the study group was higher than that of the control group,and the difference was statistically significant(P<0.05).However,there were no obvious adverse reactions in the two groups during the treatment.Conclusions:Fengsui dan and Fuzi Lizhong pills combined with conventional Western medicine can improve the total effective rate and the quality of life scores,and reduce the skin lesion scores and the serological index levels in the treatment of the acne patients with intermingled cold and heat type.Moreover,it is superior to simple conventional Western medicine treatment.
AcneIntermingled cold and heatFengsui danFuzi Lizhong pillsSkin lesionQuality of life