Predictive value of SUA and hs-CRP levels combined with Tan score for recurrent stroke in patients with acute cerebral infarction after intravenous thrombolysis
Objective:To investigate predictive value of serum uric acid(SUA)and high-sensitivity C-reactive protein(hs-CRP)levels combined with CT angiography(CTA)cerebral collateral circulation(Tan)score for recurrent stroke in patients with acute cerebral infarction after intravenous thrombolysis.Methods:The clinical data of 126 patients with acute cerebral infarction who received intravenous thrombolysis in this hospital from January 2021 to June 2022 were retrospectively analyzed.These patients were followed up for 12 months after discharge.Then,these patients were divided into recurrent group and non-recurrent group according to whether they had recurrent stroke.The levels of SUA and hs-CRP as well as the Tan score were compared between the two groups.The receiver operating characteristic(ROC)curve was used to analyze their predictive value single and combined detection of three indicators for recurrent stroke in the patients with acute cerebral infarction treated with intravenous thrombolysis.Results:After intravenous thrombolytic therapy in the 126 patients with acute cerebral infarction,31 patients had recurrent stroke,with a recurrence rate of 24.60%(31/126).The levels of SUA and hs-CRP in the recurrent group were higher than those in the non-recurrent group,the Tan score was lower than that in the non-recurrent group,and the differences were statistically significant(P<0.05).ROC curve analysis showed that the area under the curve of single and combined detection of SUA and hs-CRP levels and Tan score in the prediction of recurrent stroke in the patients with acute cerebral infarction after intravenous thrombolysis were 0.833,0.824,0.756 and 0.935,respectively.The predictive value of combined detection was the highest,which was higher than that of single detection.Conclusions:The predictive value of SUA and hs-CRP levels combined with Tan score for recurrent stroke in the patients with acute cerebral infarction after intravenous thrombolysis is higher than that of the three single tests.
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