Predictive value of combined detection of serum amylase and ApoB/ApoA1 levels on admission for severe acute pancreatitis
Objective:To observe predictive value of combined detection of serum amylase and apolipoprotein B(ApoB)/apolipoprotein A1(ApoA1)levels on admission for severe acute pancreatitis(AP).Methods:The clinical data of 86 patients with AP admitted to the hospital from December 2020 to December 2023 were retrospectively analyzed.According to whether they developed severe AP after admission,they were divided into severe group(n=40)and non-severe group(n=46).The levels of serum amylase and ApoB/ApoA1 in the two groups were detected at admission.The receiver operating characteristic(ROC)curve was used to analyze the predictive value of single and combined detection of serum amylase and ApoB/ApoA1 levels for severe AP.Results:The levels of serum amylase and ApoB/ApoA1 in the severe group were higher than those in the non-severe group,and the differences were statistically significant(P<0.05).The ROC curve showed that the value of combined detection of serum amylase and ApoB/ApoA1 levels at admission in the prediction of severe AP[area under the curve(AUC)=0.821]was higher than that of single prediction(AUC=0.795,0.740,respectively).Conclusions:The value of combined detection of serum amylase and ApoB/ApoA1 levels on admission in the prediction of severe AP is higher than that of single prediction.
Severe acute pancreatitisAmylaseApolipoprotein BApolipoprotein A1DetectionDiagnosisEfficiency