首页|入院时血清淀粉酶、ApoB/ApoA1水平联合检测对重症急性胰腺炎的预测价值

入院时血清淀粉酶、ApoB/ApoA1水平联合检测对重症急性胰腺炎的预测价值

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目的:观察入院时血清淀粉酶、载脂蛋白B(ApoB)/载脂蛋白A1(ApoA1)水平联合检测对重症急性胰腺炎(AP)的预测价值.方法:回顾性分析 2020 年 12 月至 2023 年 12 月该院收治的 86 例AP患者的临床资料,按入院后是否发展为重症AP分为重症组(n=40)和非重症组(n=46),检测两组入院时血清淀粉酶、ApoB/ApoA1 水平,并采用受试者工作特征(ROC)曲线,分析血清淀粉酶、ApoB/ApoA1 水平单项及联合检测对重症AP的预测价值.结果:重症组入院时血清淀粉酶、ApoB/ApoA1 水平均高于非重症组,差异有统计学意义(P<0.05);ROC曲线结果显示,入院时血清淀粉酶、ApoB/ApoA1水平联合检测预测重症AP的价值[曲线下面积(AUC)=0.821]高于二者单项预测(AUC=0.795、0.740).结论:入院时血清淀粉酶、ApoB/ApoA1 水平联合检测预测重症AP的价值高于二者单项预测.
Predictive value of combined detection of serum amylase and ApoB/ApoA1 levels on admission for severe acute pancreatitis
Objective:To observe predictive value of combined detection of serum amylase and apolipoprotein B(ApoB)/apolipoprotein A1(ApoA1)levels on admission for severe acute pancreatitis(AP).Methods:The clinical data of 86 patients with AP admitted to the hospital from December 2020 to December 2023 were retrospectively analyzed.According to whether they developed severe AP after admission,they were divided into severe group(n=40)and non-severe group(n=46).The levels of serum amylase and ApoB/ApoA1 in the two groups were detected at admission.The receiver operating characteristic(ROC)curve was used to analyze the predictive value of single and combined detection of serum amylase and ApoB/ApoA1 levels for severe AP.Results:The levels of serum amylase and ApoB/ApoA1 in the severe group were higher than those in the non-severe group,and the differences were statistically significant(P<0.05).The ROC curve showed that the value of combined detection of serum amylase and ApoB/ApoA1 levels at admission in the prediction of severe AP[area under the curve(AUC)=0.821]was higher than that of single prediction(AUC=0.795,0.740,respectively).Conclusions:The value of combined detection of serum amylase and ApoB/ApoA1 levels on admission in the prediction of severe AP is higher than that of single prediction.

Severe acute pancreatitisAmylaseApolipoprotein BApolipoprotein A1DetectionDiagnosisEfficiency

冯黎黎

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遂平县人民医院检验科,河南 驻马店 463100

重症急性胰腺炎 淀粉酶 载脂蛋白B 载脂蛋白A1 检测 诊断 效能

2024

中国民康医学
中国社会工作协会

中国民康医学

影响因子:0.649
ISSN:1672-0369
年,卷(期):2024.36(19)
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